Results 191 to 200 of about 266,382 (322)

Survey of the coding region of the HERG gene in long QT syndrome reveals six novel mutations and an amino acid polymorphism with possible phenotypic effects [PDF]

open access: gold, 2000
Päivi Laitinen   +7 more
openalex   +1 more source

Acute Hypokalemia May Not Be an Effective Way to Sensitize the In Situ Canine Heart for Sparfloxacin-Induced Long QT Syndrome

open access: yesJournal of Pharmacological Sciences, 2006
.: Extents of the sparfloxacin (3 – 10 mg/kg, i.v.)-induced QT interval prolongation under normokalemic and hypokalemic conditions were assessed in halothane-anesthetized beagle dogs (n = 5).
Katsuyoshi Chiba   +4 more
doaj  

Case series: Potential use of guanfacine for safer management of behavioral disturbances in patients with dementia

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 4, Issue 2, June 2025.
Abstract Background Behavioral and psychological symptoms of dementia (BPSD), including irritability, agitation, and anxiety, are common and cause significant distress for both patients and caregivers. These symptoms are linked to caregiver distress and early institutionalization, with disruptive behaviors like aggression often leading to emergency ...
Jeong Hoo Lee, Joji Suzuki
wiley   +1 more source

Clarithromycin Versus Azithromycin for Community‐Acquired Pneumonia and the Risk of Major Adverse Cardiovascular Events: A Multicentre Cohort Study Using Data From Canada and Denmark

open access: yesPharmacoepidemiology and Drug Safety, Volume 34, Issue 6, June 2025.
ABSTRACT Background Studies suggest that clarithromycin is associated with an increased risk of major adverse cardiovascular events (MACE) among adults with coronary artery disease. However, data comparing clarithromycin to other macrolides, such as azithromycin, in a broader population are lacking.
Theis Skovsgaard Itenov   +14 more
wiley   +1 more source

Psychotropic Polypharmacy and QT Prolonging Medications in Hospitalized Patients

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT It is common for patients with mental illnesses to be prescribed multiple psychotropic medications to effectively manage their conditions. Psychotropic polypharmacy has been shown to potentiate and increase the risks of several adverse effects, including QT prolongation. This study aimed to investigate the prescribing trends of and differences
Joel Moore   +7 more
wiley   +1 more source

NovelKCNQ1 mutations associated with recessive and dominant congenital long QT Syndromes: Evidence for variable hearing phenotype associated with R518X [PDF]

open access: gold, 2000
Jian Wei   +4 more
openalex   +1 more source

Large‐Scale Analysis of Age and Sex Effects on Corrected QT and JT Intervals: Insights From Hospital‐Based Controls and Moxifloxacin‐Treated Cases

open access: yesClinical and Translational Science, Volume 18, Issue 6, June 2025.
Large‐scale analysis establishes age‐ and sex‐specific QTc/JTc reference ranges, quantifying their distinct impacts in controls and moxifloxacin‐treated cases. ABSTRACT The corrected QT (QTc) interval is a critical marker for assessing proarrhythmic potential in drug development, while the corrected JT (JTc) interval provides specific insight into ...
Eunwoo Kim   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy