Results 141 to 150 of about 217,364 (264)

The interplay of ageing and rheumatic diseases

The Lancet. Healthy Longevity
The Lancet Healthy Longevity
doaj   +1 more source

Correction: From sick care to healthspan: educating the longevity physician for health maintenance and health promotion. [PDF]

Biogerontology
Thor D, Barzilai D, Lyu YX, Spiru L.
europepmc   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Defining obesity to improve ageing

The Lancet. Healthy Longevity
The Lancet Healthy Longevity
doaj   +1 more source

A longitudinal analysis of quality and longevity of mental health apps indexed in MIND, the largest database. [PDF]

World Psychiatry
Herpertz J, Dwyer B, Mikkleson J, Flathers M, Opel N, Otte C, Gold SM, Ebner-Priemer UW, Schwarz J, Linardon J, Egbejoda A, Ryan S, Torous J.   +12 more
europepmc   +1 more source

Cobalt Single‐Atom Catalysts for Ultrafast Sulfamethoxazole Degradation: Unveiling the Chloride‐Ion‐Enhanced Formation of Co(IV)=O

Advanced Science, EarlyView.
An atomically dispersed Co–N4 single‐atom catalyst rapidly activates peroxymonosulfate to remove the antibiotic sulfamethoxazole from water. Common ions have little impact, but chloride dramatically speeds degradation by promoting a high‐valent Co(IV) = O oxidant via in situ HOCl–catalyst electron transfer.
Anting Ding, Jing Lu, Yafei Fan, Chenyu Zeng, Yuhang Lin, Yufei Shi, Zulin Zhang   +6 more
wiley   +1 more source

Leadership – can you be too old?

The Lancet. Healthy Longevity
The Lancet Healthy Longevity
doaj   +1 more source

Bat-Inspired Longevity: Immune Damage Management and Nutritional Modulation for Healthy Aging. [PDF]

Int J Mol Sci
Park S, Daily JW.
europepmc   +1 more source

Rational Design of Weakly‐Solvating Molecules for Salt‐In‐Pre‐Ionic‐Liquid Electrolytes for Li Metal Batteries

Advanced Science, EarlyView.
The weakly‐solvating TFMSPyr electrolyte tailors the Li+ solvation structure by suppressing solvent coordination and promoting anion‐dominated solvation. This unique solvation environment induces preferential anion decomposition at electrode interfaces, forming robust inorganic rich S/CEI.
Bishnu P. Thapaliya, Vaidyanathan Sethuraman, Naresh C. Osti, Arvind Ganesan, K. Shawn Reeves, Michael J. Zachman, Albina Y. Borisevich, Harry M. Meyer III, Xiao‐Guang Sun, Eugene Mamontov, Lei Cheng, Sheng Dai   +11 more
wiley   +1 more source

Longevity Aesthetics: A Conceptual Framework for Integrating Pro-Aging Medicine Into Surgical and Nonsurgical Practice. [PDF]

Aesthet Surg J Open Forum
Haykal D, Nahai F.
europepmc   +1 more source