Results 231 to 240 of about 241,449 (302)

Ultrafast Multilevel Switching and Synaptic Behavior in a Planar Quantum Topological Memristor

Advanced Science, EarlyView.
Dry‐transferred Bi2Te3 layers enable a planar quantum topological memristor framework. In‐plane topological surface states facilitate ultrafast & low‐power operations. Coexisting analog and digital modes support current‐controlled multilevel states. PQTM exhibits 105 s retention, 103 cycles endurance, and reproducibility across 24 devices.
Mamoon Ur Rashid, Usman Safder, Sobia Ali Khan, Anh‐Tuan Pham, Muhammad Sheeraz, Nguyen‐Hoang Dang, Duy Le Thanh, Zeeshan Tahir, Faisal Maqbool, Koo‐Hyun Chung, Sunglae Cho, Jungdae Kim, Yong Soo Kim   +12 more
wiley   +1 more source

Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli

Advanced Science, EarlyView.
An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng, Hao Liu, Haolin Han, Meng Meng, Shaojie Wang, Tianwei Tan, Haijia Su   +6 more
wiley   +1 more source

Combining the Pitcher and Lotus Plant: Supericephobic and Superhydrophobic Silicone Films

Advanced Science, EarlyView.
Based on bench‐top nanomolding of polydimethylsiloxane (PDMS) with optimized silicone oil content, we developed hierarchically structured silicone films by essentially combining the properties of the lotus and pitcher plant; particularly we are able to achieve water contact angle as high as 171° and ice adhesion strength as low as 11.5 kPa (i.e ...
Cliff L. W. Ng, Joshua Ham, Sanpreet Kaur, Clayton W. Schultz, Hua‐Zhong Yu   +4 more
wiley   +1 more source

How We Sleep, How We Move, How Long We Expect to Live: An Integrative Review of Lifestyle Behaviors and Subjective Life Expectancy. [PDF]

Nutrients
Pătru O, Păunescu A, Bena A, Luca S, Văcărescu C, Ciornei AI, Virtosu M, Enache B, Luca CT, Crisan S.   +9 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Multilayered regulation of longevity in Caenorhabditis elegans. [PDF]

Mol Cells
Bong D, Kwon HC, Lee SV.
europepmc   +1 more source

Dendritic Nano‐Based Slippery Coating by Synergistic Mechanical and Electrostatic Interactions with Persistent and Exceptional Combats Thrombosis

Advanced Science, EarlyView.
A novel dendritic nano‐based slippery coating (DNSC), fabricated by encapsulating carboxyl silicone oil within amino dendritic silica nanoparticles and co‐embedding them in an epoxy resin matrix. The dendritic architecture enhances nanoparticle dispersion in the matrix and establishes mechanical interlock.
Shu Zhang, Yao Shen, Juan Liu, Qing Zeng, Yunze Ma, Shuping Chen, Taiyu Nan, Xiaoying Qiu, Jiayi Yu, Tao Fan, Guozhi Huang, Jihua Zou, Chengduan Yang   +12 more
wiley   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

Ewa Bomba-Warczak, Karen M Velez, Luhan T. Zhou, Christelle Guillermier, Seby Edassery, Matthew L. Steinhauser, Jeffrey N. Savas, Francesca E. Duncan   +7 more
openalex   +1 more source

Neutrophil‐Mimetic Nanoscavengers Target the Inflammatory Microenvironment to Eliminate NETs/ROS and Immunomodulate cGAS‐STING Signaling in Septic AKI

Advanced Science, EarlyView.
Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang, Chenxi Zhang, Ranran Luo, Qiuchi Wu, Pengchen Ren, Xinyu Liu, Yingying Luo, Zhongsheng Xu, Xiaojing He, Yun Liu   +9 more
wiley   +1 more source