Results 21 to 30 of about 371,915 (351)

Analysis of Longevity Traits in Holstein Cattle: A Review

open access: yesFrontiers in Genetics, 2021
Dairy cow longevity is an essential economic trait that can supplement the breeding value of production traits, which is related to the herd time and lifetime milk yield of dairy cows.
Honghong Hu   +4 more
semanticscholar   +1 more source

Molecular and environmental factors regulating seed longevity.

open access: yesBiochemical Journal, 2020
Seed longevity is a central pivot of the preservation of biodiversity, being of main importance to face the challenges linked to global climate change and population growth.
J. Zinsmeister, O. Leprince, J. Buitink
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

A novel benchmark for COVID-19 pandemic testing effectiveness enables the accurate prediction of new Intensive Care Unit admissions

open access: yesScientific Reports, 2021
The positivity rate of testing is currently used both as a benchmark of testing adequacy and for assessing the evolution of the COVID-19 pandemic. However, since the former is a prerequisite for the latter, its interpretation is often conflicting.
Dimitris Nikoloudis   +2 more
doaj   +1 more source

Beyond longevity: healthy longevity [PDF]

open access: yesThe Lancet Healthy Longevity, 2021
Alain, Putot   +3 more
openaire   +2 more sources

Invited review: Academic and applied approach to evaluating longevity in dairy cows.

open access: yesJournal of Dairy Science, 2020
In its simplest form, longevity is defined as the ability to live a long life. Within the dairy industry, longevity has been defined and measured in many different ways, and the aim of this review is to disentangle the definitions and provide some ...
J. C. Schuster   +4 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Adapting Blood DNA Methylation Aging Clocks for Use in Saliva Samples With Cell-type Deconvolution

open access: yesFrontiers in Aging, 2021
DeepMAge is a deep-learning DNA methylation aging clock that measures the organismal pace of aging with the information from human epigenetic profiles.
Fedor Galkin   +5 more
doaj   +1 more source

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