Results 21 to 30 of about 730,309 (342)
eLife, 2020 Worms with increased levels of the epigenetic mark H3K9me2 have a longer lifespan that can be passed down to future generations.
Felicity Emerson +2 more
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The evolution of longevity [PDF]
Current Biology, 2002 According to the evolutionary theory of ageing, genes will not evolve for the purpose of promoting ageing. Moreover, the mutation–accumulation theory predicts that mutations in different genes will cause ageing in different evolutionary lineages. However, as discussed, empirical evidence does not generally support mutation–accumulation as a mechanism ...
David Gems, Linda Partridge
openaire +3 more sources
Still living with mortality: The longevity risk transfer market after one decade [PDF]
, 2019 This paper updates Living with Mortality published in 2006. It describes how the longevity risk transfer market has developed over the intervening period, and, in particular, how insurance-based solutions – buy-outs, buy-ins and longevity insurance ...
Biffis +37 more
core +2 more sources
Pupal and Adult Parameters as Potential Indicators of Cottonwood Leaf Beetle (Coleoptera: Chrysomelidae) Fecundity and Longevity [PDF]
, 2018 Cottonwood leaf beetle, Chrysomela scripta, pupae from a laboratory colony were weighed and monitored through adult emergence, oviposition, and mortality to determine if correlations existed between various pupal or adult parameters and fecundity or ...
Coyle, David R +2 more
core +3 more sources
Delayed Germination of Seeds: A Look at the Effects of Adult Longevity, the Timing of Reproduction, and Population Age/Stage Structure [PDF]
, 1994 The effects of adult longevity, the timing of reproduction, and population age/stage structure on the evolution of seed dormancy are explored in both constant and variable environment models. In the constant environment models complete germination is the
Rees, M.
core +1 more source
Longevity and mortality of owned dogs in England [PDF]
, 2013 Improved understanding of longevity represents a significant welfare opportunity for the domestic dog, given its unparalleled morphological diversity.
Brodbelt, D C +5 more
core +2 more sources
Single and cross-generation natural hedging of longevity and financial risk [PDF]
, 2012 The paper provides natural hedging strategies among death benefits and annuities written on a single and on different generations. It obtains closed-form Delta and Gamma hedges, in the presence of both longevity and interest rate risk.
Luciano, Elisa +2 more
core +2 more sources
Cell Reports, 2012 Controversy has recently arisen over the role of sirtuins in metazoan aging. In this issue of Cell Reports, Banerjee et al. demonstrate that Drosophila Sir2 is necessary for life span extension in response to dietary restriction and that its overexpression in the fat body increases the life span.
David A. Sinclair, Eric Verdin
openaire +4 more sources
Mortality-Indexed Annuities [PDF]
, 2009 Longevity risk has become a major challenge for governments, individuals, and annuity providers in most countries, and especially its aggregate form, i.e.
Richter, Andreas, Weber, Frederik
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Heat shock factor 1 mediates the longevity conferred by inhibition of TOR and insulin/IGF-1 signaling pathways in C. elegans [PDF]
, 2019 Target of rapamycin (TOR) signaling is an evolutionarily well-conserved pathway that regulates various physiologic processes, including aging and metabolism. One of the key downstream components of TOR signaling is ribosomal protein S6 kinase (S6K) whose
daeeun jeong +5 more
core +1 more source