Results 21 to 30 of about 770,943 (358)
Translational immune and metabolic markers of aging in dogs
Scientific ReportsDogs serve as a promising aging model due to their genetic diversity, condensed lifespan, and shared living environment with humans. Alterations in the immune and metabolic parameters are hallmarks of aging in humans, but few studies have investigated ...
James E. McMahon +9 more
doaj +1 more source
, 2017 Shane Kimura ’78 celebrates his 40th and final season as volleyball head ...
Linfield Magazine Staff
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Beyond longevity: healthy longevity [PDF]
The Lancet Healthy Longevity, 2021 Alain, Putot +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Adapting Blood DNA Methylation Aging Clocks for Use in Saliva Samples With Cell-type Deconvolution
Frontiers in Aging, 2021 DeepMAge is a deep-learning DNA methylation aging clock that measures the organismal pace of aging with the information from human epigenetic profiles.
Fedor Galkin +5 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Longevity gene responsible for robust blue organic materials employing thermally activated delayed fluorescence [PDF]
, 2023 Qingyu Meng +7 more
openalex +1 more source
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
Scientific ReportsChronic feeding of a high fat diet (HFD) in preclinical species induces broad metabolic dysfunction characterized by body weight gain, hyperinsulinemia, dyslipidemia and impaired insulin sensitivity.
Matthew Peloquin +8 more
doaj +1 more source