Results 31 to 40 of about 810,836 (243)

In Vitro Comparative Evaluation of Newly Produced Desensitizer, Chlorhexidine and Gluma on Bond Strength and Bond Longevity of Composite to Dentin

Journal of Dentistry, 2020
Statement of the Problem: Etching process on dentin can activate matrix metalloproteinase (MMP) which hydrolyze organic matrix of demineralized dentin. Gluma and chlorhexidine could inhibit the activation of MMP.
Reza Davalloo , Seyedeh Maryam Tavangar , Heshmatollah Ebrahimi , Farideh Darabi, Shima Mahmoudi   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Should we Subsidize Longevity? [PDF]

This paper studies the design of the optimal non linear taxation in an economy where longevity varies across agents, and depends on three factors: longevity genes, health investment and farsightedness.
Marie-Louise Leroux, Pierre Pestieau, Grégory Ponthiere   +2 more
core   +4 more sources

Bayesian Integrated Nested Laplace Approximation (INLA) Longevity Bonds Market Model

Risks
Pricing coupon longevity bonds (CLBs) is challenging in illiquid markets due to the incompleteness of insurance markets and the unavailability of longevity payout data.
Yethu Sithole, Samuel Asante Gyamerah
doaj   +1 more source

Single and cross-generation natural hedging of longevity and financial risk [PDF]

, 2012
The paper provides natural hedging strategies among death benefits and annuities written on a single and on different generations. It obtains closed-form Delta and Gamma hedges, in the presence of both longevity and interest rate risk.
Regis, Luca, Elisa Luciano, Luca Regis, Vigna, Elena, Luciano, Elisa, Elena Vigna   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Dentists' performance in dentin-composite resin bonding before and after hands-on course learning

Journal of the Formosan Medical Association, 2020
Background/Purpose: The restoration longevity depends on a high dentin-composite bond quality. This study investigated learning outcomes when using etch-and-rinse and self-etch adhesives among general practitioners in a hands-on bonding test course ...
Yu-Hsin Huang, Yin-Lin Wang, Po-Yen Lin, Yu-Jung Lai, Chun-Wen Cheng, Yu-Chih Chiang   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Comparative Evaluation of Shear Bond Strength of Resin Modified Glass Ionomer Cement and Biodentine as Dentin Substitutes to Bonded Silver Amalgam and Composite Resin [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: The bond strength between the restorative material and the tooth, as well as between the restorative material and the base, is an important factor and can determine the longevity of a dental treatment.
Riddhi Thakkar, Sandya Kini, Nagaraja P Upadhya   +2 more
doaj   +1 more source