Results 21 to 30 of about 5,661,149 (260)

Multivariate Risk-Neutral Pricing of Reverse Mortgages under the Bayesian Framework

Risks, 2019
In this paper, we suggest a Bayesian multivariate approach for pricing a reverse mortgage, allowing for house price risk, interest rate risk and longevity risk.
Jackie Li, Atsuyuki Kogure, Jia Liu
doaj   +1 more source

Familial longevity is marked by lower diurnal salivary cortisol levels: the leiden longevity study [PDF]

, 2012
Background Reported findings are inconsistent whether hypothalamic-pituitary-adrenal (HPA) signaling becomes hyperactive with increasing age, resulting in increasing levels of cortisol.
Westendorp, Rudi G J, Oei Nicole Y. L., Maier, Andrea B., Jansen, Steffy W M, Maier, A.B., de Craen, Anton J M, Akintola, Abimbola A., Pijl Hanno, Noordam, Raymond, Slagboom, P. Eline, Hanno Pijl, Diana van Heemst, Raymond Noordam, Jansen, SWM, Westendorp, RGJ, van der Grond Jeroen, Westendorp Rudi G. J., van Heemst, Diana, P Eline Slagboom, Noordam, R., Steffy W M Jansen, Heemst, D. van, Leiden Longevity Study group, Craen, A.J.M. de, van der Grond, J, Oei, Nicole YL, Jeroen van der Grond, van Heemst Diana, Anton J M de Craen, de Craen Anton J. M., Jansen, S.W.M., van Heemst, D, Noordam, R, de Craen, AJM, Akintola Abimbola A., Grond, J. van der, Pijl, Hanno, Oei, N.Y.L., Maier, Andrea B.; id_orcid, Rudi G J Westendorp, Maier, AB, Maier Andrea B., Pijl, H., Leiden Longevity Study Grp, Slagboom, PE, Noordam Raymond, Nicole Y L Oei, Jansen, Steffy, Slagboom, P.E., de Craen, Anton JM, Oei, Nicole Y L, Andrea B Maier, Jansen Steffy W. M., Oei, NYL, Westendorp, R.G.J., van der Grond, Jeroen, Akintola, Abimbola A, Abimbola A Akintola, Slagboom P. Eline, Akintola, A.A., Akintola, AA, Maier, Andrea B, Westerndorp, Rudi GJ, Pijl, H   +63 more
core   +1 more source

Uncertainty in Pricing and Risk Measurement of Survivor Contracts

Risks
As life expectancy increases, pension plans face growing longevity risk. Standardized longevity-linked securities such as survivor contracts allow pension plans to transfer this risk to capital markets.
Kenrick Raymond So, Stephanie Claire Cruz, Elias Antonio Marcella, Jeric Briones, Len Patrick Dominic Garces   +4 more
doaj   +1 more source

Designing Annuities with Flexibility Opportunities in an Uncertain Mortality Scenario

Risks, 2021
We consider annuity designs in which the benefit amount is allowed to fluctuate (up or down), based on a given mortality/longevity experience. This way, guarantees are relaxed in respect of traditional annuity arrangements.
Annamaria Olivieri
doaj   +1 more source

Guaranteed Annuity Option Under Correlated and Regime-Switching Risks

Risks
Guaranteed annuity options (GAOs) allow policyholders to convert accumulated funds into life annuities at maturity at a guaranteed minimum rate. Thus, insurers are exposed to both investment and longevity risks.
Jude Martin B. Grozen, Rogemar S. Mamon
doaj   +1 more source

Can Pension Funds Partially Manage Longevity Risk by Investing in a Longevity Megafund?

Risks, 2018
Pension funds, which manage the financing of a large share of global retirement schemes, need to invest their assets in a diversified manner and over long durations while managing interest rate and longevity risks.
Edouard Debonneuil, Anne Eyraud-Loisel, Frédéric Planchet   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

An Indexation Mechanism for Retirement Age: Analysis of the Gender Gap

Risks, 2019
The management of National Social Security Systems is being challenged more and more by the rapid ageing of the population, especially in the industrialized countries.
Mariarosaria Coppola, Maria Russolillo, Rosaria Simone   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Selection on Alleles Affecting Human Longevity and Late-Life Disease: The Example of Apolipoprotein E [PDF]

, 2010
It is often claimed that genes affecting health in old age, such as cardiovascular and Alzheimer diseases, are beyond the reach of natural selection. We show in a simulation study based on known genetic (apolipoprotein E) and non-genetic risk factors ...
Kirkwood Thomas B. L., Drenos Fotios, Drenos, F, Kirkwood, TBL, Fotios Drenos, Thomas B L Kirkwood   +5 more
core   +1 more source