Results 41 to 50 of about 410,288 (305)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Partial splitting of longevity and financial risks: The longevity nominal choosing swaptions [PDF]
Insurance: Mathematics and Economics, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Bensusan, Harry +3 more
openaire +3 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
The Cost of Counterparty Risk and Collateralization in Longevity Swaps [PDF]
, 2014 Derivative longevity risk solutions, such as bespoke and indexed longevity swaps, allow pension schemes, and annuity providers to swap out longevity risk, but introduce counterparty credit risk, which can be mitigated if not fully eliminated by ...
Bacinello +28 more
core +1 more source
Guaranteed Annuity Option Under Correlated and Regime-Switching Risks
RisksGuaranteed annuity options (GAOs) allow policyholders to convert accumulated funds into life annuities at maturity at a guaranteed minimum rate. Thus, insurers are exposed to both investment and longevity risks.
Jude Martin B. Grozen, Rogemar S. Mamon
doaj +1 more source
The Investigation of a Forward-Rate Mortality Framework
Risks, 2019 Stochastic mortality models have been developed for a range of applications from demographic projections to financial management. Financial risk based models built on methods used for interest rates and apply these to mortality rates.
Daniel H. Alai +2 more
doaj +1 more source
Longevity risk—Its financial impact on pensions
Scientific African, 2022 We study the financial impact of longevity risk on defined benefit (DB) pension plan liabilities using the 2010 Ghana population census, and the Lee-Carter model. We compare the usual Lee-Carter model to an extended version. While we observe that Ghana’s
Nana Poku Appiagyei Nantwi +2 more
doaj +1 more source
Longevity risk and capital markets: the 2021–22 update
Journal of Demographic Economics, 2023 AbstractThis special issue of the Journal of Demographic Economics contains 10 contributions to the academic literature all dealing with longevity risk and capital markets. Draft versions of the papers were presented at Longevity 16: The Sixteenth International Longevity Risk and Capital Markets Solutions Conference that was held in Helsingør near ...
Blake, D. +3 more
openaire +5 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Risk Equity: A New Proposal [PDF]
, 2007 What does distributive justice require of risk regulators? Various executive orders enjoin health and safety regulators to take account of “distributive impacts,” “equity,” or “environmental justice,” and many scholars endorse these requirements.
Adler, Matthew D.
core +3 more sources