Results 101 to 110 of about 33,267,872 (251)

Impact of remnant cholesterol on short-term mortality in acute decompensated heart failure: cohort study evidence from Jiangxi, China

Frontiers in Endocrinology
IntroductionRemnant cholesterol (RC), a highly atherogenic lipid component, has been strongly implicated in the pathogenesis and adverse clinical outcomes of numerous cardiovascular and cerebrovascular diseases.
Guoan Jian, Guoan Jian, Guoan Jian, Kun Jiang, Kun Jiang, Kun Jiang, Zihao Lu, Zihao Lu, Zihao Lu, Shiming He, Shiming He, Shiming He, Lin Xie, Shuhua Zhang, Qun Wang, Hengcheng Lu, Zhiyu Xiong, Zhiting Wu, Guobo Xie, Guotai Sheng, Aimin Xie, Yanfeng Liu, Wei Wang, Yang Zou   +23 more
doaj   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

COVID-19 Survey in Five National Longitudinal Cohort Studies: Millennium Cohort Study, Next Steps, 1970 British Cohort Study and 1958 National Child Development Study, 2020-2021

, 2020
copyright UK Data Service and data collection copyright owner.The Centre for Longitudinal Studies (CLS) and the MRC Unit for Lifelong Health and Ageing (LHA) have carried out two online surveys of the participants of five national longitudinal cohort ...
University College London, UCL Institute of Education, Centre for Longitudinal Studies
core  

Analysis of TNF-antagonist switch over time and associated risk factors in the Swiss Inflammatory Bowel Disease Cohort

, 2014
BACKGROUND AND AIMS Limited data from large cohorts are available on tumor necrosis factor (TNF) antagonists (infliximab, adalimumab, certolizumab pegol) switch over time.
Safroneeva, Ekaterina, Safroneeva, E., Rogler, Gerhard, Schöpfer, Alain, Pittet, V., Vavricka, Stephan, Pittet, Valérie, Fournier, N., Hiroz, Philippe, Swiss Inflammatory Bowel Disease Cohort Study Group, Rogler, G., Fournier, Nicolas, Schoepfer, A.M., Swiss Inflammatory Bowel Diseases Cohort Study Group, The, Vavricka, S.R., Juillerat, Pascal, Hiroz, P., Vavricka, Stephan R, Schoepfer, Alain M   +18 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Incidence and sequence of scoliosis and windswept hip deformity: which comes first in 4148 children with cerebral palsy? A longitudinal cohort study

BMC Musculoskeletal Disorders
Background The aim was to analyse whether scoliosis or windswept hip deformity (WSH) occurs first for children with cerebral palsy (CP). Methods This longitudinal cohort study using data from 1994 − 2020 (26 years) involved 41,600 measurements of 4148 ...
Jackie Casey, Andreas Rosenblad, Atli Agustsson, Henrik Lauge-Pedersen, Elisabet Rodby-Bousquet   +4 more
doaj   +1 more source

Association of metabolic syndrome severity with cognitive decline among Chinese older adults: evidence from two prospective cohort studies

Frontiers in Neuroscience
IntroductionThe relationship between metabolic syndrome (MetS) severity and cognitive decline is not well understood, largely because the traditional binary diagnosis of MetS is unable to capture its continuous nature.MethodsThis longitudinal study ...
Ming Chen, Ming Chen, Lu Liu, Lu Liu, Na Liu, Na Liu, Ji-Wen Che, Ji-Wen Che, Yuan-Yuan Peng, Yuan-Yuan Peng, Yan Zeng, Yan Zeng   +11 more
doaj   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source