Results 91 to 100 of about 2,996,820 (336)

Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut   +11 more
wiley   +1 more source

jmcm: An R Package for Joint Mean-Covariance Modeling of Longitudinal Data

open access: yesJournal of Statistical Software, 2017
Longitudinal studies commonly arise in various fields such as psychology, social science, economics and medical research, etc. It is of great importance to understand the dynamics in the mean function, covariance and/or correlation matrices of repeated ...
Jianxin Pan, Yi Pan
doaj   +1 more source

Compensating for Missing Data from Longitudinal Studies Using WinBUGS [PDF]

open access: yes
Missing data is a common problem in survey based research. There are many packages that compensate for missing data but few can easily compensate for missing longitudinal data.
Adrian G. Barnett   +3 more
core   +1 more source

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo   +11 more
wiley   +1 more source

Gender emancipation and its impact on happiness: An examination of the happy wife, happy life formula

open access: yesInterdisciplinary Journal of Sociality Studies
The adage "happy wife, happy life" implies that women's gender emancipation could contribute to the overall societal quality of life. However, it raises at least two questions: Does advancing women's rights lead to increased happiness for women?
Renier Steyn
doaj   +1 more source

A Bayesian model for longitudinal circular data [PDF]

open access: yes
The analysis of short longitudinal series of circular data may be problematic and to some extent has not been completely developed. In this paper we present a Bayesian analysis of a model for such data.
Eduardo Gutiérrez-Peña   +1 more
core  

Continuous Monitoring of Bladder Dysfunction in People With Multiple Sclerosis: Wearables for the Bladder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Bladder dysfunction affects over 85% of people with multiple sclerosis (PwMS), yet current assessment methods are limited to periodic in‐clinic evaluations or subjective patient reports, failing to capture real‐world symptom fluctuations.
Valerie J. Block   +8 more
wiley   +1 more source

Cervical Spinal Cord Magnetization Transfer Ratio and Its Relationship With Clinical Outcomes in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The cervical spinal cord (cSC) is highly relevant to clinical dysfunction in multiple sclerosis (MS) but remains understudied using quantitative magnetic resonance imaging (MRI). We assessed magnetization transfer ratio (MTR), a semi‐quantitative MRI measure sensitive to MS‐related tissue microstructural changes, in the cSC and its ...
Lisa Eunyoung Lee   +26 more
wiley   +1 more source

Variational Inference of Joint Models using Multivariate Gaussian Convolution Processes

open access: yes, 2019
We present a non-parametric prognostic framework for individualized event prediction based on joint modeling of both longitudinal and time-to-event data.
Kontar, Raed, Yue, Xubo
core  

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