Results 71 to 80 of about 1,469,254 (314)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Modelling longitudinal cognitive test data with ceiling effects and left skewness

Frontiers in Applied Mathematics and Statistics
Cognitive tests such as the Mini Mental State Examination (MMSE) may result in data with discrete and skewed distributions that necessitate proper statistical models for valid inference.
Denitsa Grigorova, Denitsa Grigorova, Dean Palejev, Dean Palejev, Ralitza Gueorguieva, for the Alzheimer's Disease Neuroimaging Initiative   +5 more
doaj   +1 more source

The Australian Longitudinal Study on Women's Health: 1973-78 cohort Core Data Release, Survey 7 data, 2015

, 2020
The Australian Longitudinal Study on Women's Health (ALSWH) is a longitudinal population-based survey, first funded in 1995, which examines the health of over 57,000 Australian women.
Mishra, Gita, Tooth, Leigh, Byles, Julie, Loxton, Deborah, Australian Government Department of Health   +4 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Variance component estimates applying random regression models for test-day milk yield in Caracu heifers (Bos taurus Artiodactyla, Bovidae)

Genetics and Molecular Biology, 2008
Random regression models (RRM) were used to estimate covariance functions for 2,155 first-lactation milk yields of native Brazilian Caracu heifers. The models included contemporary group (defined as year-month of test and paddock) fixed effects, and ...
Lenira El Faro, Vera Lucia Cardoso, Lucia Galvão de Albuquerque   +2 more
doaj   +1 more source

The Australian Longitudinal Study on Women's Health: 1973-78 cohort Core Data Release, Survey 5 data, 2009

, 2020
The Australian Longitudinal Study on Women's Health (ALSWH) is a longitudinal population-based survey, first funded in 1995, which examines the health of over 57,000 Australian women.
Tooth, Leigh, Commonwealth Government Department of Health and Ageing, Lee, Christina, Dobson, Annette, Brown, Wendy, Byles, Julie, Lucke, Jayne, Loxton, Deborah, Sibbritt, David, Pachana, Nancy   +9 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Impact of environmental factors in predicting daily severity scores of atopic dermatitis

Clinical and Translational Allergy, 2021
Background Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects 20% of children worldwide. Environmental factors including weather and air pollutants have been shown to be associated with AD symptoms.
Guillem Hurault, Valentin Delorieux, Young‐Min Kim, Kangmo Ahn, Hywel C. Williams, Reiko J. Tanaka   +5 more
doaj   +1 more source

Quantitative Longitudinal Data Analysis

, 2020
First published Open Access under a Creative Commons license as What is Quantitative Longitudinal Data Analysis?, this title is now also available as part of the Bloomsbury Research Methods series.
Lambert, Paul, Gayle, Vernon
core  

The Australian Longitudinal Study on Women's Health: 1921-26 cohort Core Data Release, Survey 1 data, 1996

, 2020
The Australian Longitudinal Study on Women's Health (ALSWH) is a longitudinal population-based survey, first funded in 1995, which examines the health of over 57,000 Australian women.
Commonwealth Government Department of Health and Ageing, Dobson, Annette, Mandelson, Lenore, Byles, Julie, Schofield, Margot, Bryson, Lois, Williams, Gail   +6 more
core   +1 more source