Results 71 to 80 of about 3,225,781 (282)

jmcm: An R Package for Joint Mean-Covariance Modeling of Longitudinal Data

open access: yesJournal of Statistical Software, 2017
Longitudinal studies commonly arise in various fields such as psychology, social science, economics and medical research, etc. It is of great importance to understand the dynamics in the mean function, covariance and/or correlation matrices of repeated ...
Jianxin Pan, Yi Pan
doaj   +1 more source

Longitudinal evidence of the impact of normal thyroid stimulating hormone variations on cognitive functioning in very old age [PDF]

open access: yes, 2008
The purpose of this study was to examine longitudinal associations among thyroid stimulating hormone (TSH) levels and cognitive performance. Data collected at the first three assessment times, approximately 3 years apart, are reported for the survivors ...
Bunce, D, Wahlin, A, Wahlin, TBR
core  

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham   +7 more
wiley   +1 more source

Attrition in longitudinal household survey data [PDF]

open access: yes
Longitudinal household data can have considerable advantages over much more widely used cross-sectional data. The collection of longitudinal data, however, may be difficult and expensive.
Alderman, Harold   +4 more
core  

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

The non-communicable disease e-Cohort for hypertension in Latin America: concept, survey development and study protocol

open access: yesGlobal Health Action
Non-communicable diseases like hypertension cause substantial morbidity and mortality in low- and middle-income countries, where limited access to high-quality care contributes to millions of preventable deaths annually. Traditional assessments of health
Patricia J. Garcia   +9 more
doaj   +1 more source

LINDA - Longitudinal INdividual DAta for Sweden [PDF]

open access: yes
This paper presents LINDA - a register-based longitudinal data set for Sweden. LINDA consists of a large panel of individuals, and their household members, which is representative for the population during the period 1960 to 1998.
Edin, Per-Anders, Fredriksson, Peter
core  

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

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