Results 61 to 70 of about 1,469,254 (314)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The Australian Longitudinal Study on Women's Health: 1989-95 cohort Core Data Release, Survey 2 data, 2014

, 2020
The Australian Longitudinal Study on Women's Health (ALSWH) is a longitudinal population-based survey, first funded in 1995, which examines the health of over 57,000 Australian women.
Mishra, Gita, Tooth, Leigh, Tavener, Meredith, Byles, Julie, Lucke, Jayne, Loxton, Deborah, Sibbritt, David, Pachana, Nancy, McLaughlin, Deirdre, Australian Government Department of Health, Powers, Jennifer   +10 more
core   +1 more source

The Australian Longitudinal Study on Women's Health: 1973-78 cohort Core Data Release, Survey 8 data, 2018

, 2022
The Australian Longitudinal Study on Women's Health (ALSWH) is a longitudinal population-based survey, first funded in 1995, which examines the health of over 57,000 Australian women.
Mishra, Gita, Tooth, Leigh, Byles, Julie, Loxton, Deborah, Australian Government Department of Health   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The Australian Longitudinal Study on Women's Health: 1946-51 cohort Core Data Release, Survey 3 data, 2001

, 2020
The Australian Longitudinal Study on Women's Health (ALSWH) is a longitudinal population-based survey, first funded in 1995, which examines the health of over 57,000 Australian women.
Mishra, Gita, Commonwealth Government Department of Health and Ageing, Lee, Christina, Kenardy, Justin, Dobson, Annette, Warner Smith, Penny, Brown, Wendy, Byles, Julie, Young, Anne, Schofield, Margot, Bryson, Lois   +10 more
core   +1 more source

Bayesian discrimination with longitudinal data [PDF]

Biostatistics, 2001
The motivation for the methodological development is a double-blind clinical trial designed to estimate the effect of regular injection of growth hormone, with the purpose of identifying growth hormone abusers in sport. The data formed part of a multicentre investigation jointly sponsored by the European Union and the International Olympic Committee ...
P J, Brown, M G, Kenward, E E, Bassett
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

BIRESPONSE SPLINE TRUNCATED NONPARAMETRIC REGRESSION MODELING FOR LONGITUDINAL DATA ON MONTHLY STOCK PRICES OF THREE PRIVATE BANKS IN INDONESIA

Barekeng
This study investigates the application of a truncated spline nonparametric regression model for biresponse analysis of longitudinal data, focusing on modeling monthly stock prices specifically opening and closing prices of three private banks in ...
Reza Pahlepi, Idhia Sriliana, Winalia Agwil, Cinta Rizki Oktarina   +3 more
doaj   +1 more source

The Australian Longitudinal Study on Women's Health: 1973-78 cohort Core Data Release, Survey 4 data, 2006

, 2020
The Australian Longitudinal Study on Women's Health (ALSWH) is a longitudinal population-based survey, first funded in 1995, which examines the health of over 57,000 Australian women.
Tooth, Leigh, Commonwealth Government Department of Health and Ageing, Lee, Christina, Warner Smith, Penny, Byles, Julie, Lucke, Jayne, Loxton, Deborah, Young, Anne, Brown, Wendy J, Dobson, Annette J., Bryson, Lois   +10 more
core   +1 more source

Ignorability for general longitudinal data [PDF]

Biometrika, 2017
Likelihood factors that can be disregarded for inference are termed ignorable. We demonstrate that close ties exist between ignorability and identification of causal effects by covariate adjustment. A graphical condition, stability, plays a role analogous to that of missingness at random, but is applicable to general longitudinal data.
Farewell, D. M., Huang, C., Didelez, V.
openaire   +4 more sources