Results 51 to 60 of about 3,402,219 (239)

Multiphonon longitudinal wobbling in 127Xe

open access: yesPhysics Letters B, 2020
A family of four odd parity bands in 127Xe has been investigated via in-beam γ-ray spectroscopy and conclusive evidence for the first and second phonon longitudinal wobbling excitations has been found.
S. Chakraborty   +15 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Single Longitudinal Mode Optofluidic Microring Laser Based on a Hollow-Core Microstructured Optical Fiber

open access: yesIEEE Photonics Journal, 2017
A single longitudinal mode microring dye laser based on a simplified hollow-core microstructured optical fiber (SHMOF) is proposed and demonstrated. The dye laser uses a submicron thickness silica microring embedded in the SHMOF as resonator and has the ...
Jie Yu   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Raman signatures of alkyl chain length: Comparative analysis of 1-alkanols and normal alkanes

open access: yesResults in Chemistry
The comparative experimental and density functional theory studies of Raman spectra of 1-alkanols (CnH2n+1OH with n = 2–16) and n-alkanes (CnH2n+2 with n = 5–24) are presented.
Vladimir V. Kuzmin   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Coupling effects of beam-beam interaction and longitudinal impedance

open access: yesPhysical Review Accelerators and Beams, 2022
Recent studies have shown a novel coherent head-tail instability induced by beam-beam interaction with a large Piwinski angle. The instability has become an important issue during the designs of CEPC and FCC-ee. Simulations have further revealed that the
Chuntao Lin, Kazuhito Ohmi, Yuan Zhang
doaj   +1 more source

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