Results 71 to 80 of about 1,824,593 (305)

Predicting patient ‘cost blooms’ in Denmark: a longitudinal population-based study [PDF]

BMJ Open, 2017
Objectives To compare the ability of standard versus enhanced models to predict future high-cost patients, especially those who move from a lower to the upper decile of per capita healthcare expenditures within 1 year—that is, ‘cost bloomers’. Design
Tamang, Suzanne, Milstein, Arnold, Sorensen, Henrik Toft, Pedersen, Lars, Mackey, Lester, Betterton, Jean-Raymond, Janson, Lucas, Shah, Nigam   +7 more
openaire   +3 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Employer Size Effects in Russia [PDF]

, 2000
As early as 1911, Henry L. Moore documented that the wages of female textile workers in Italy were higher in larger establishments. In the last thirty years a large number of studies have demonstrated the presence of employer size-wage effects (at both ...
Idson, Todd
core   +2 more sources

Association of Genetic Risk for Schizophrenia With Nonparticipation Over Time in a Population-Based Cohort Study [PDF]

, 2016
Progress has recently been made in understanding the genetic basis of schizophrenia and other psychiatric disorders. Longitudinal studies are complicated by participant dropout, which could be related to the presence of psychiatric problems and ...
Davey Smith, George, Hubbard, Leon, Martin, Joanna, O'Donovan, Michael C, Stergiakouli, Evangelia, Thapar, Anita, Tilling, Kate M, Zammit, Stanley   +7 more
core   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Sexual orientation and symptoms of common mental disorder or low wellbeing: combined meta-analysis of 12 UK population health surveys [PDF]

, 2016
Background Previous studies have indicated increased risk of mental disorder symptoms, suicide and substance misuse in lesbian, gay and bisexual (LGB) adults, compared to heterosexual adults.
A Chakraborty, B Everett, B Needham, D Chae, DJ Lick, G Knies, G Meckler, Gareth Hagger-Johnson, H Williams, Health and Social Care Information Centre, Health and Social Care Information Centre, Health and Social Care Information Centre, I Meyer, I Meyer, J Almeida, J Brazier, J Elliott, J-W Weenink, Joanna Semlyen, Justin Varney, K McLaughlin, L Durso, L Lindley, L Wichstrøm, M Hatzenbuehler, M King, M Rosario, M Rosario, Michael King, Office of National Statistics, P Kind, P Serrano-Aguilar, Public Health England, T Debray, T Sandfort   +34 more
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Evaluating health effects of transport interventions: methodologic case study [PDF]

, 2006
Background: There is little evidence about the effects of environmental interventions on population levels of physical activity. Major transport projects may promote or discourage physical activity in the form of walking and cycling, but researching the ...
Mitchell, R., Mutrie, N., Ogilvie, D., Petticrew, M., Platt, S.   +4 more
core   +1 more source

The Impact of PhD Studies on Mental Health-A Longitudinal Population Study

Journal of Health Economics
Recent self-reported and cross-sectional survey evidence documents high levels of mental health problems among PhD students. We study the impact of PhD studies on mental health care uptake using Swedish administrative records of prescriptions for psychiatric medication for the full population of PhD students. First, we provide descriptive evidence that
Bergvall, Sanna, Fernström, Clara, Ranehill, Eva, Sandberg, Anna   +3 more
openaire   +3 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source