Results 21 to 30 of about 1,192,915 (258)

Risk factors relate to the variability of health outcomes as well as the mean: A GAMLSS tutorial

open access: yeseLife, 2022
Background: Risk factors or interventions may affect the variability as well as the mean of health outcomes. Understanding this can aid aetiological understanding and public health translation, in that interventions which shift the outcome mean and ...
David Bann, Liam Wright, Tim J Cole
doaj   +1 more source

Weakening of the cognition and height association from 1957 to 2018: Findings from four British birth cohort studies

open access: yeseLife, 2023
Background: Taller individuals have been repeatedly found to have higher scores on cognitive assessments. Recent studies have suggested that this association can be explained by genetic factors, yet this does not preclude the influence of environmental ...
David Bann   +3 more
doaj   +1 more source

Changes in knee extension peak torque and body composition and their relationship with change in gait speed

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2019
Background Slow gait speed is a powerful predictor of disability in activities of daily living and mortality. Muscle strength and body composition change over time, but their changes differ by sex.
Yusuke Osawa   +4 more
doaj   +1 more source

Inequality in hospitalization due to non-communicable diseases in Sweden: Age-cohort analysis of the Uppsala Birth Cohort Multigenerational Study

open access: yesSSM: Population Health, 2021
We aimed to investigate cohort differences in age trajectories of hospitalization due to non-communicable conditions, and if these varied by paternal socioeconomic position.
Dawid Gondek   +5 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian   +13 more
wiley   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi   +10 more
wiley   +1 more source

Describing the geographical linkage between the UK Millennium Cohort Study and crime incidents in England and Wales

open access: yesInternational Journal of Population Data Science
Background Enhancing longitudinal cohort studies by linking routine external data to them is increasingly used to evaluate how local environments impact participants' outcomes (e.g.
Nicolas Libuy   +2 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar   +7 more
wiley   +1 more source

The Effect of Targeted Incentives on Response Rates and Representativeness: Evidence From the Next Steps Age 32 Survey

open access: yesSurvey Research Methods
This paper analyses the effect on response rate and non-response bias of tailoring the level of monetary incentives offered to participants in a longitudinal study, depending on sample members’ response propensity. Specifically, we test whether offering
Alessandra Gaia   +4 more
doaj   +1 more source

Socioeconomic inequalities in blood pressure: co-ordinated analysis of 147,775 participants from repeated birth cohort and cross-sectional datasets, 1989 to 2016

open access: yesBMC Medicine, 2020
Background High blood pressure (BP) is a key modifiable determinant of cardiovascular disease and a likely determinant of other adverse health outcomes.
David Bann   +3 more
doaj   +1 more source

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