Results 31 to 40 of about 1,291,137 (259)

Factors associated with pneumococcal vaccination uptake in over 50s in Ireland: a cross-sectional study using results from the Irish Longitudinal Study on Ageing (TILDA)

BMJ Public Health
Introduction Pneumococcal vaccination is a key global health strategy to reduce the morbidity and mortality associated with pneumococcal disease.Methods This study examined the factors associated with pneumococcal vaccination uptake in community-dwelling
Rose Anne Kenny, Cathal McCrory, Siobhan Scarlett, Kevin Organ, Sinead Mc Loughlin, Ann Hever   +5 more
doaj   +1 more source

Longitudinal grip strength is associated with susceptibility to the Sound Induced Flash Illusion in older adults

Aging Brain, 2023
The precision of temporal multisensory integration is associated with specific aspects of physical functioning in ageing, including gait speed and incidents of falling. However, it is unknown if such an association exists between multisensory integration
A. O' Dowd, R.J. Hirst, A. Setti, R.A. Kenny, F.N. Newell   +4 more
doaj   +1 more source

Adherence to the European Society of Cardiology hypertension guidelines over 12 years of follow-up in the Irish population

Open Heart
Background Hypertension is a significant risk factor for cardiovascular disease, dementia and chronic kidney disease (CKD). Older adults bear the brunt of these conditions, and managing hypertension can be especially challenging in this cohort.
John William McEvoy, Rose Anne Kenny, Donal J Sexton, Cathal McCrory, Siobhan Scarlett, Robert Briggs, Caoimhe McGarvey   +6 more
doaj   +1 more source

Syncope, Fear of Falling and Quality of Life Among Older Adults: Findings From the Irish Longitudinal Study on Aging (TILDA)

Frontiers in Cardiovascular Medicine, 2020
Objective: Syncope is a prevalent condition that has a marked impact on quality of life. We examined the association between syncope and quality of life (QoL) and whether this association was explained by fear of falling (FoF).Methods: We examined data ...
Kevin McCarthy, Kevin McCarthy, Mark Ward, Román Romero Ortuño, Román Romero Ortuño, Rose Anne Kenny, Rose Anne Kenny   +6 more
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

De noodzaak van veerkracht

Tijdschrift voor Gerontologie en Geriatrie, 2015
Veel onderzoek binnen de gerontologie en de geriatrie is gericht op uitkomsten die te maken hebben met ziekte en beperkingen. Dat is logisch; ouderdom hangt samen met een hoog risico op een grote hoeveelheid lichamelijke en mentale gezondheidsproblemen.
Martijn Huisman
doaj   +1 more source

Association between vitamin D deficiency and the risk of prevalent type 2 diabetes and incident prediabetes: A prospective cohort study using data from The Irish Longitudinal Study on Ageing (TILDA)

EClinicalMedicine, 2022
Summary: Background: It is hypothesized that vitamin D contributes to the aetiology of type 2 diabetes mellitus (diabetes). This study's objective was to examine the relationships between baseline vitamin D status (as measured by plasma 25 ...
Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Cathal Walsh, Martin Healy, Annette L. Fitzpatrick, James B. Walsh, Belinda Hernández, Padraic Fallon, Anne M. Molloy, Rose Anne Kenny   +10 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Structural brain signatures of frailty, defined as accumulation of self-reported health deficits in older adults

Frontiers in Aging Neuroscience, 2023
BackgroundFrailty in older adults has been associated with reduced brain health. However, structural brain signatures of frailty remain understudied. Our aims were: (1) Explore associations between a frailty index (FI) and brain structure on magnetic ...
Raquel Gutiérrez-Zúñiga, James R. C. Davis, James R. C. Davis, Kathy Ruddy, Céline De Looze, Céline De Looze, Daniel Carey, James Meaney, Rose Anne Kenny, Rose Anne Kenny, Rose Anne Kenny, Silvin Paul Knight, Silvin Paul Knight, Roman Romero-Ortuno, Roman Romero-Ortuno, Roman Romero-Ortuno, Roman Romero-Ortuno   +16 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source