Results 81 to 90 of about 33,901,282 (286)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Harmonised Mental Health Measures at Age 10/11 in Selected British Cohorts: Millennium Cohort Study

, 2022
copyright UK Data Service and data collection copyright owner.CLOSER (Cohort and Longitudinal Studies Enhancement Resources) aims to maximise the use, value and impact of longitudinal studies, both at home and abroad.
Cohort and Longitudinal Studies Enhancement Resources
core   +2 more sources

Harmonised Mental Health Measures at Age 10/11 in Selected British Cohorts: National Child Development Study

, 2022
copyright UK Data Service and data collection copyright owner.CLOSER (Cohort and Longitudinal Studies Enhancement Resources) aims to maximise the use, value and impact of longitudinal studies, both at home and abroad.
Cohort and Longitudinal Studies Enhancement Resources
core   +2 more sources

Risk factors for young people not being in education, employment or training (NEET): Longitudinal analyses over a 10 year follow up period in Scotland

International Journal of Population Data Science, 2018
Background The high level of young people who are NEET has been an important long-standing issue in Scotland. Having been NEET has several long term detrimental effects. Identifying risk factors of becoming NEET may inform interventions aimed at reducing
Dawn Everington, Zhiqiang Feng, Kevin Ralston, Chris Dibben   +3 more
doaj   +1 more source

Longitudinal studies are required [PDF]

Journal of the Royal Society of Medicine, 2015
Naseer, Ahmad, G Neil, Thomas, Paramjit, Gill, Colin, Chan, Francesco, Torella   +4 more
openaire   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Edited by Alan Barrett, George Savva, Virpi Timonen and Rose Anne Kenny

, 2011
The Irish Longitudinal Study on Ageing (TILDA) is a large-scale, nationally representative study of people aged 50 and over in Ireland. It is the most ambitious study of ageing ever carried out in Ireland and represents a step-change in terms of data,
Burke, Helen, McGee, Hannah, Normand, Charles, Savva, George, Barrett, Alan, Layte, Richard, Maty, Siobhán, Whelan, Brendan, Cronin, Hilary, Hickey, Anne, Kenny, Rose Anne, Morgan, Karen, Mosca, Irene, O'Sullivan, Vincent, Kamiya, Yumiko, O'Regan, Claire, Sofroniou, Nick, Timonen, Virpi   +17 more
core  

The Office for National Statistics Longitudinal Study

International Journal of Population Data Science, 2019
Background and Rationale The ONS Longitudinal Study (‘the LS’) covers England and Wales and includes individual data from the 1971 – 2011 decennial censuses and linked information on births, deaths and cancer registrations.
Alison Sizer, Oliver Duke-Williams
doaj   +1 more source