Neurosarcoidosis presenting as longitudinally extensive transverse myelitis
Journal of Clinical Neuroscience, 2009Neurosarcoidosis is an uncommon clinical entity, even in patients with systemic sarcoidosis. Its presentation is widely varied but longitudinally extensive transverse myelitis secondary to neurosarcoidosis has only rarely been described. We report the case of a patient with pulmonary sarcoidosis and congenital immunosuppression who developed ...
Rachel, Dolhun, S, Sriram
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Dengue-associated longitudinally extensive transverse myelitis
BMJ Case ReportsWe diagnosed a patient with dengue fever who developed acute onset of sensorimotor quadriparesis with bladder involvement, and facial nerve involvement. Despite initial negative results in routine investigations and cerebrospinal fluid analysis, spinal MRI confirmed longitudinally extensive transverse myelitis.
Naresh Kumar +3 more
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Primary spinal oligoastrocytoma mimicking longitudinally extensive transverse myelitis
Multiple Sclerosis and Related Disorders, 2015Longitudinally extensive transverse myelitis (LETM) is most commonly associated with neuromyelitis optica spectrum disorders (NMOSD). However, a wide range of etiologies may produce longitudinally extensive spinal cord lesions (LESCLs) on imaging. We highlight the case of a patient with a spinal cord tumor whose imaging showed LESCL and was diagnosed ...
T R, Yeo +4 more
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Longitudinal Extensive Transverse Myelitis following T-ALL
Neuropediatrics, 2016Background/Purpose: Acute transverse myelitis is an acquired demyelinating disease of the central nervous system with different etiologies. Besides infections autoimmune demyelination plays a major role. Clinical presentation includes motor, sensory and autonomic symptoms.
V. Kraus +7 more
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A Case of Longitudinally Extensive Transverse Myelitis
2018Primary CNS angiitis (PACNS) is distinguished from other vasculitides by its exclusive involvement of the CNS, generally in a multifocal manner. Lesions are typically, but not invariably, ischemic or hemorrhagic. Symptoms most frequently include headache, but also commonly involve cognitive impairment, focal neurological symptoms, and sometimes ...
Aaron E. Miller +3 more
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Neuromyelitis optica spectrum disorders: beyond longitudinally extensive transverse myelitis
Clinical Radiology, 2015To describe the neuroradiological features and their prevalence in patients with neuromyelitis optica (NMO).Two neuroradiologists independently reviewed 35 spinal cord and 37 brain MRI studies from patients with NMO. The examinations were analysed for the presence of lesion, topography, enhancement, and brain lesions suggestive of multiple sclerosis ...
Lemos, M. D. UNIFESP +5 more
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Idiopathic aquaporin-4 antibody negative longitudinally extensive transverse myelitis
Multiple Sclerosis Journal, 2014Background: Longitudinally extensive transverse myelitis (LETM) is a characteristic manifestation of neuromyelitis optica (NMO). However, not all patients with LETM are positive for aquaporin-4 (AQP4) antibodies. We evaluated the characteristics of idiopathic isolated LETM negative for AQP4 antibodies.
Jae-Won, Hyun +8 more
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Diagnostic approach of patients with longitudinally extensive transverse myelitis
Acta Neurologica Belgica, 2012The aim of this study is to present a diagnostic and therapeutic approach in patients with LETM. In a period between June 2008 and June 2010, all patients who fulfilled criteria for LETM were included in the study. All patients underwent a standardized protocol of investigations presented in this paper.
Habek, Mario +3 more
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Longitudinally extensive transverse myelitis after Campylobacter jejuni enteritis
Practical Neurology, 2017Campylobacter jejuni infection is well-known to precipitate Guillain-Barré syndrome through an immune-mediated attack on the peripheral nervous system. Molecular mimicry between C. jejuni lipo-oligosaccharides on the surface of infectious agents and human gangliosides in the peripheral nerves induces cross-reactive immune responses ...
Yudy, Llamas +3 more
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Longitudinal extensive transverse myelitis—it's not all neuromyelitis optica
Nature Reviews Neurology, 2011Longitudinal extensive transverse myelitis (LETM) is defined as a spinal cord lesion that extends over three or more vertebrae, as seen on MRI of the spine. The clinical presentation of a patient with LETM is often dramatic and can consist of paraparesis or tetraparesis, sensory disturbances, and gait, bladder, bowel and/or sexual dysfunction.
Corinna, Trebst +6 more
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