Results 181 to 190 of about 129,087 (309)

Supporting Looked After Children and Care Leavers In Decreasing Drugs, and alcohol (SOLID): protocol for a pilot feasibility randomised controlled trial of interventions to decrease risky substance use (drugs and alcohol) and improve mental health of looked after children and care leavers aged 12-20 years. [PDF]

Pilot Feasibility Stud, 2017
Alderson H, McGovern R, Brown R, Howel D, Becker F, Carr L, Copello A, Fouweather T, Kaner E, McArdle P, McColl E, Shucksmith J, Steele A, Vale L, Lingam R.   +14 more
europepmc   +1 more source

Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Irritability is a prevalent and impairing feature associated with autism, yet remains poorly understood, particularly in adults. Drawing heavily on insights translated from pediatric and transdiagnostic literatures, we propose that irritability in autistic individuals often reflects a psychophysiological stress or threat response, rooted in a ...
Hsiang‐Yuan Lin, Arthur N. Westover, Amy S. F. Lutz, Manish K. Jha   +3 more
wiley   +1 more source

Providing sex and relationships education for looked-after children: a qualitative exploration of how personal and institutional factors promote or limit the experience of role ambiguity, conflict and overload among caregivers. [PDF]

BMJ Open, 2019
Nixon C, Elliott L, Henderson M.
europepmc   +1 more source

Linking Brain Morphometry to Psychometric Measures and Energy‐Metabolic Biomarkers in Adults With Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is associated with differences in neurodevelopment and altered metabolism, yet the interplay between brain morphometry, mitochondrial and energy metabolism biomarkers, and autistic traits in adults remains poorly understood. This study investigates the link between brain structure, psychometric measures, and both
Eleonora Esposto, Kathrin Nickel, Dominique Endres, Kimon Runge, Katharina Domschke, Thomas Lange, Marco Reisert, Anke Schumann, Cinzia Niolu, Ludger Tebartz van Elst, Simon Maier   +10 more
wiley   +1 more source

Challenges to undertaking randomised trials with looked after children in social care settings. [PDF]

Trials, 2015
Mezey G, Robinson F, Campbell R, Gillard S, Macdonald G, Meyer D, Bonell C, White S.   +7 more
europepmc   +1 more source

A Large‐Scale Study on the Relation Between Multilingualism and Social Traits in Adults With and Without Autism Diagnoses

Autism Research, EarlyView.
ABSTRACT Autism Spectrum Disorder is a neurodevelopmental condition characterized by persistent difficulties in social interaction and communication alongside restricted, repetitive patterns of behavior, interests, or activities. Emerging evidence suggests that bi/multilingualism may enhance social interaction skills, yet prior research has largely ...
Margreet Vogelzang, Sean Dong Wei Gan, Jamie Setch   +2 more
wiley   +1 more source

Smoking and Looked-After Children: A Mixed-Methods Study of Policy, Practice, and Perceptions Relating to Tobacco Use in Residential Units. [PDF]

Int J Environ Res Public Health, 2016
Huddlestone L, Pritchard C, Ratschen E.
europepmc   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Exploring new avenues: Psychedelic‐assisted therapy for young people

British Journal of Clinical Pharmacology, EarlyView.
Rates of mental illness in young people are increasing, whereas the development of novel mental health treatments has not significantly progressed. Psychedelic‐assisted therapy, using substances such as psilocybin and 3,4‐methylenedioxymethamphetamine (MDMA), has shown potential in the treatment of mental illnesses in the adult population, including ...
Ioanna Artemis Vamvakopoulou, Dasha Nicholls, David J. Nutt, Martina Di Simplicio   +3 more
wiley   +1 more source

Accessing hard to reach groups, travelers and looked after children. [PDF]

Hum Vaccin Immunother, 2013
Print F.
europepmc   +1 more source