Results 41 to 50 of about 784,546 (249)

Association of childhood out-of-home care status with all-cause mortality up to 42-years later: Office of National Statistics Longitudinal Study

open access: yesBMC Public Health, 2020
Background The adverse life-long consequences of being looked-after as a child are well recognised, but follow-up periods for mortality risk have mostly ended in young adulthood and mortality suggested to differ by age of placement, gender and cohort in ...
Emily T. Murray   +3 more
doaj   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

open access: yesAdvanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu   +7 more
wiley   +1 more source

A commitment to care: residential child care work in England

open access: yesScottish Journal of Residential Child Care, 2003
Residential child care is a valuable and complex job. It requires a wide range of skills, and can make a huge difference to the lives of some of our most vulnerable young people. So why are there high levels of vacancies and staff turnover in residential
Amanda Mainey
doaj   +1 more source

Biosecurity Primitive: Polymerase X‐based Genetic Physical Unclonable Functions

open access: yesAdvanced Science, EarlyView.
What if every cell line can carry an unforgeable genomic fingerprint—one that proves its origin, ensures its authenticity, and thwarts unauthorized duplication? Here, CRISPR‐induced DNA lesions paired with TdT‐mediated repair produce robust, unique, and unclonable genetic signatures—advancing the concept of molecular Physical Unclonable Functions (PUF)
Zikun Zhou   +7 more
wiley   +1 more source

Children's social works statistics (incorporating the children's looked after statistics)

open access: yesScottish Journal of Residential Child Care, 2015
On 31 March the Scottish Government published official statistics about children and young people who were 'looked after' by (or in receipt of aftercare services from) Scottish local authorities, over the year from 01 August 2013 to 31 July 2014.
Ben Farrugia
doaj   +1 more source

Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang   +4 more
wiley   +1 more source

Revitalising residential and foster care: new horizons in the 21st Century: 7th EUSARF International Congess, Trondheim, Norway, 11 – 14 September 2002

open access: yesScottish Journal of Residential Child Care, 2003
The European Scientific Association for Residential and Foster Care for Children and Adolescents (EUSARF) held its 7th International Congress in the ancient Norwegian capital of Trondheim.
Kirstie Maclean
doaj   +1 more source

BRD4 Signaling Maintains the Differentiated State of β Cells

open access: yesAdvanced Science, EarlyView.
The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu   +22 more
wiley   +1 more source

How can the bird that is born for joy sit in a cage and sing?

open access: yesScottish Journal of Residential Child Care, 2014
This article provides an insight into being a Reader-in-Residence with The Reader Organisation. It describes work to encourage reading with children in a Glasgow primary school.
Patrick Fisher
doaj   +1 more source

Increasing sedentary time, minimum dietary energy requirements, and food security assessment

open access: yesApplied Economic Perspectives and Policy, EarlyView.
Abstract We compute corrections for sedentary behavior in physical activity levels (PALs) and incorporate them along with corrections for over estimation of basal metabolic rates (BMRs) into threshold caloric intakes, known as minimum dietary energy requirements (MDERs).
Jacob Michels   +2 more
wiley   +1 more source

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