Results 41 to 50 of about 1,233,327 (309)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The value of resilience as a concept for practice in residential settings

open access: yesScottish Journal of Residential Child Care, 2003
Resilience is a concept that is increasingly gaining currency as a basis for practice with children and young people. The concept, however, is not easy to define and the term is often used loosely or uncritically so that the implications for practice are
Brigid Daniel
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Guest Editorial Vol2 no2

open access: yesScottish Journal of Residential Child Care, 2003
After just over 3 years as Director of the Scottish Institute for Residential Child Care (SIRCC), I am returning to work in the Social Work Services Inspectorate. This has caused me to reflect on whether anything has changed in residential care over that
Kirstie Maclean
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Children's social works statistics (incorporating the children's looked after statistics)

open access: yesScottish Journal of Residential Child Care, 2015
On 31 March the Scottish Government published official statistics about children and young people who were 'looked after' by (or in receipt of aftercare services from) Scottish local authorities, over the year from 01 August 2013 to 31 July 2014.
Ben Farrugia
doaj   +1 more source

Mind-mindedness in parents of looked-after children. [PDF]

open access: yesDevelopmental Psychology, 2017
The studies reported here aimed to test the proposal that mind-mindedness is a quality of personal relationships by assessing mind-mindedness in caregiver-child dyads in which the relationship has not spanned the child's life or in which the relationship has been judged dysfunctional.
Fishburn, Sarah Louise   +8 more
openaire   +7 more sources

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Revitalising residential and foster care: new horizons in the 21st Century: 7th EUSARF International Congess, Trondheim, Norway, 11 – 14 September 2002

open access: yesScottish Journal of Residential Child Care, 2003
The European Scientific Association for Residential and Foster Care for Children and Adolescents (EUSARF) held its 7th International Congress in the ancient Norwegian capital of Trondheim.
Kirstie Maclean
doaj   +1 more source

Understanding the educational experiences and opinions, attainment, achievement and aspirations of looked after children in Wales [PDF]

open access: yes, 2015
This report presents the findings of research that explored the educational experiences attainment and aspirations of looked after children and young people (LACYP) in Wales.
Andrews, Darren   +6 more
core   +2 more sources

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