Results 71 to 80 of about 6,582 (257)
Dementia, 2017 Background I, the 45-year-old scientist, the PhD, the sublime researcher, now subject to dementia? I felt confused, very ashamed and told no one, until they found out. I suffer from brain atrophy, associated with multiple sclerosis I am suffering from for years. My cognitive impairment is the result of my shrinking brain!
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Integrated Approach to Ship Electrification Using Fuel Cells and an Ammonia Decomposition System
Journal of Marine Science and EngineeringThis study investigates the environmental and economic performance of integrating a proton exchange membrane fuel cell, battery systems, and an organic Rankine cycle-based waste heat recovery system for ship electrification.
Onur Yuksel +9 more
doaj +1 more source
Ancient Greek Weaving, Experimental Archeology on Greek Textiles and Household GDP
EXARC Journal, 2021 This paper outlines the experimental weaving project of an ancient Greek chlamys to investigate the weaving production capacity of a typical household and reconstruct women’s contribution to household GDP in ancient Greece.
Richard J. Palmer
doaj
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Journal of EngineeringThe air permeability of the fabric is affected by the type of yarn used, the loom speed, and the amount of air pressure delivered by the relay nozzles. In this study, 21 Ne of ring and rotor spun yarns were used as a weft in an air jet loom.
Anmen Admas, Alemayehu Assefa
doaj +1 more source
EnergiesThis research aims to assess the integration of different fuel cell (FC) options with battery and waste heat recovery systems through a mathematical modelling process to determine the most feasible retrofit solutions for a marine electricity generation ...
Onur Yuksel +9 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source