Results 181 to 190 of about 48,371 (318)
环境与职业医学Water resources are crucial for environmental protection and the health of humans, plants, and animals. Contamination of water by pathogens such as bacteria, viruses, and protozoa can lead to outbreaks of various water-related infectious diseases, posing
Fubin HUANG, Eryi SHU, Hongliang FAN
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New developments in pathogen detection and identification [PDF]
, 2012 By the turn of the century most of the methods for amplifying the pathogen detection signal had already been developed. However, only a few were successfully incorporated into routine diagnosis schemes.
Nolasco, Gustavo
core
VIEW, EarlyView.(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang +9 more
wiley +1 more source
Rapid detection of Mycoplasma pneumonia by Loop mediated isothermal amplification (LAMP)
مجله دانشگاه علوم پزشکی گرگان, 2015 Background and Objective: Mycoplasma pneumoniae bacteria, is one of the most important factor in causing of respiratory infections. Serological and molecular detection methods have their own limitation.
Davudi-Asl F +2 more
doaj
VIEW, EarlyView.Turbidity‐based digital LAMP offers a low‐cost alternative for nucleic acid quantification, but interpreting bright‐field images is difficult due to weak contrast and noise. We developed NanoFuse‐YOLO11, an AI‐based detection model that automatically identifies positive reaction units in turbidity microscopy images.
Zhu Chen +7 more
wiley +1 more source
Agricultural and Forest Entomology, EarlyView.The oak processionary moth is an invasive pest in the United Kingdom that threatens biodiversity and public health, with rising control costs highlighting the need for sustainable management alternatives Conservation biocontrol using the parasitoid fly Carcelia iliaca is promising but key biological data gaps hinder evidence‐based policy development. A
Kyle Alexander Miller +5 more
wiley +1 more source
Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries
British Journal of Pharmacology, EarlyView.Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
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The FEBS Journal, EarlyView.We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
Sensing and Bio-Sensing ResearchCardiovascular disease (CVD) continues to be the leading cause of death and disability worldwide, creating a pressing need for diagnostic approaches that are rapid, sensitive, and accessible, particularly for early detection and point-of-care testing ...
Jianguang Guo +4 more
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