Results 1 to 10 of about 27,634 (161)
Isothermal Amplification Technology for Disease Diagnosis [PDF]
Biosensors, 2022 Isothermal amplification (IA) is a nucleic acid amplification technology (NAAT) that has contributed significantly to the healthcare system. The combination of NAAT with a suitable detection platform resulted in higher sensitivity, specificity, and rapid
Kiatnida Treerattrakoon +2 more
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Diagnostic Devices for Isothermal Nucleic Acid Amplification [PDF]
Sensors, 2012 Since the development of the polymerase chain reaction (PCR) technique, genomic information has been retrievable from lesser amounts of DNA than previously possible.
Chia-chen Chang +2 more
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A review of reaction enhancement strategies for isothermal nucleic acid amplification reactions
Sensors and Actuators Reports, 2021 Isothermal nucleic acid amplification techniques are used to detect a variety of molecules such as RNAs, DNAs and proteins. When compared to the gold standard polymerase chain reaction, isothermal methods are rapid and simple but often have lower ...
Stephanie McCalla, Burcu Özay
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Sensors, 2021 The easy and rapid spread of bacterial contamination and the risk it poses to human health makes evident the need for analytical methods alternative to conventional time-consuming laboratory-based techniques for bacterial detection. To tackle this demand,
Anna Toldrá +2 more
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Principles and Applications of Loop-Mediated Isothermal Amplification to Point-of-Care Tests
Biosensors, 2022 For the identification of nucleic acids, which are important biomarkers of pathogen-mediated diseases and viruses, the gold standard for NA-based diagnostic applications is polymerase chain reaction (PCR).
Jee-Woong Park
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Advances in Isothermal Amplification for the Diagnosis of Tuberculosis. [PDF]
J Clin Lab AnalABSTRACT Background Detecting tuberculosis (TB) remains challenging in low‐resource settings due to limited access to advanced diagnostic tools. The emergence of isothermal amplification techniques, such as loop‐mediated isothermal amplification (LAMP), presents a promising solution for TB ...
Jirakittiwut N, Ratthawongjirakul P.
europepmc +3 more sources
Loop-Mediated Isothermal Amplification in Schistosomiasis [PDF]
Journal of Clinical Medicine, 2021 Human schistosomiasis is one of the most important parasitic diseases, causing around 250 million cases (mostly in Africa) and 280,000–500,000 deaths every year. Due to the limited resources and the far-removed nature of many endemic areas, the implementation of new, sensitive and specific diagnostic tools has had little success.
Juan García-Bernalt Diego +4 more
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Foods, 2022 The isothermal amplification method, a molecular-based diagnostic technology, such as loop-mediated isothermal amplification (LAMP) and recombinase polymerase amplification (RPA), is widely used as an alternative to the time-consuming and labor-intensive
Ye-Ji Moon, So-Young Lee, Se-Wook Oh
doaj +1 more source
Molecular Mechanisms Underlying CRISPR/Cas-Based Assays for Nucleic Acid Detection
Current Issues in Molecular Biology, 2023 Applied to investigate specific sequences, nucleic acid detection assays can help identify novel bacterial and viral infections. Most up-to-date systems combine isothermal amplification with Cas-mediated detection.
Denis N. Antropov, Grigory A. Stepanov
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Recent Uses of Paper Microfluidics in Isothermal Nucleic Acid Amplification Tests
Biosensors, 2023 Isothermal nucleic acid amplification tests have recently gained popularity over polymerase chain reaction (PCR), as they only require a constant temperature and significantly simplify nucleic acid amplification.
Jocelyn Reynolds +4 more
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