Results 81 to 90 of about 268,099 (291)

Model checking in-the-loop: Finding counterexamples by systematic simulation [PDF]

2008 American Control Conference, 2008
Model checkers for program verification have enjoyed considerable success in recent years. In the control systems domain, however, they suffer from an inability to account for the physical environment. For control systems, simulation is the most widely used approach for validating system designs.
Flavio Lerda, James Kapinski, Hitashyam Maka, Edmund M. Clarke, Bruce H. Krogh   +4 more
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Strong coupling expansion of 12 BPS Wilson loop in SYM theory and 2-loop Green-Schwarz string in AdS5 × S5

Nuclear Physics B
The exact localization result for the expectation value of the 12 BPS circular Wilson loop in N=4 SYM theory is given in the planar limit by the famous Bessel function expression: 〈W〉=2NλI1(λ).
M. Beccaria, S.A. Kurlyand, A.A. Tseytlin   +2 more
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Integrating Loop Acceleration Into Bounded Model Checking

AbstractBounded Model Checking (BMC) is a powerful technique for proving unsafety. However, finding deep counterexamples that require a large bound is challenging for BMC. On the other hand, acceleration techniques compute “shortcuts” that “compress” many execution steps into a single one.
Florian Frohn, Jürgen Giesl
openaire   +3 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Worm Monte Carlo study of the honeycomb-lattice loop model

, 2011
We present a Markov-chain Monte Carlo algorithm of "worm"type that correctly simulates the O(n) loop model on any (finite and connected) bipartite cubic graph, for any real n>0, and any edge weight, including the fully-packed limit of infinite edge ...
Batchelor, Batchelor, Batchelor, Baxter, Baxter, Baxter, Blöte, Blöte, Cardy, Chayes, Coddington, Deng, Deng, Deng, Deng, Deng, Di Francesco, Diestel, Ding, Domany, Dubail, Duplantier, Fortuin, Grimmett, Guo, Holm, Jacobsen, Jacobsen, Janke, Jian-Sheng, Kager, Karowski, Kondev, Kunz, Landau, Mansfield, Mohar, Mohar, Nienhuis, Nienhuis, Nienhuis, Oberdorf, Pelissetto, Potts, Prokof'ev, Qingquan Liu, Saleur, Sokal, Stanley, Suzuki, Sweeny, Swendsen, Timothy M. Garoni, Wolff, Wu, Wu, Youjin Deng, Zhang, Zhang   +58 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Bounded Model Checking of ETL Cooperating with Finite and Looping Automata Connectives [PDF]

Journal of Applied Mathematics, 2013
As a complementary technique of the BDD-based approach, bounded model checking (BMC) has been successfully applied to LTL symbolic model checking. However, the expressiveness of LTL is rather limited, and some important properties cannot be captured by such logic.
Rui Wang, Wanwei Liu, Tun Li, Xiaoguang Mao, Ji Wang   +4 more
openaire   +3 more sources

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source