Decoding RNA Structural Ensembles: Energy Landscape Exploration of the TAR Stemloop. [PDF]
J Chem Theory ComputRöder K.
europepmc +1 more source
Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease
Advanced Science, EarlyView.This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang +15 more
wiley +1 more source
Long-term susceptible fractions in networked epidemic models and their relation to the basic reproduction number. [PDF]
Sci RepKhong SZ, Su L, Georgiou T.
europepmc +1 more source
Isosteric Substitution Enables Rational Design of Two‐Dimensional Energetic Crystals
Advanced Science, EarlyView.Isosteric substitution transforms a classical nitro–amine motif into two‐dimensional aminofurazans with performance beyond TATB. ABSTRACT Two‐dimensional (2D) energetic crystals dissipate mechanical insult via interlayer slip, yet their molecular design space remains narrow.
Linyuan Wen +6 more
wiley +1 more source
WatCon: A Python Tool for Analysis of Conserved Water Networks Across Protein Families. [PDF]
JACS AuBrownless AR +2 more
europepmc +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
Advanced Science, EarlyView.In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
RGB image encryption using SPN with a novel block cipher over simple graph adjacency matrices and Galois fields. [PDF]
Sci RepSajjad M, Alqwaifly NA.
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The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models
Advanced Science, EarlyView.Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková +5 more
wiley +1 more source
The promise and challenge of spatial inference with the full ancestral recombination graph under Brownian motion. [PDF]
G3 (Bethesda)Deraje P, Kitchens J, Coop G, Osmond MM.
europepmc +1 more source