Results 81 to 90 of about 1,349,598 (293)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The loop-tree duality at work

open access: yes, 2014
We review the recent developments of the loop-tree duality method, focussing our discussion on analysing the singular behaviour of the loop integrand of the dual representation of one-loop integrals and scattering amplitudes. We show that within the loop-
Bierenbaum, Isabella   +5 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The (1,0) tensor and hypermultiplets in loop space

open access: yesJournal of High Energy Physics
We show that the (1,0) tensor and hypermultiplet supersymmetry variations can be uplifted to loop space. Upon dimensional reduction we make contact with abelian five-dimensional super Yang-Mills, which has a nonabelian generalization that we subsequently
Dongsu Bak, Andreas Gustavsson
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Primitive loop spaces

open access: yesTopology, 1968
OUR OBJECTIVE in this note is to prove the following special case of a theorem of Browder [0]: THEOREM. Suppose that X is a simply connected Hopf space and p is an odd prime. Then if H*@X; ZlpZ) is primitively generated it is free commutative. Actually as the proof will show we can replace the condition that X is a Hopf space with the weaker condition ...
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Representations of the $SU(N)$ $T$-algebra and the loop representation in $1+1$-dimensions

open access: yes, 1993
We consider the phase-space of Yang-Mills on a cylindrical space-time ($S^1 \times {\bf R}$) and the associated algebra of gauge-invariant functions, the $T$-variables.
Anderson A   +8 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Glass fiber-reinforced composite resin as a space maintainer: A clinical study

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2008
The aim of this study is to evaluate the use of glass fiber-reinforced composite resin (GFRCR) as a space maintainer and to compare it with a conventional band-and-loop space maintainer.
Subramaniam P, Babu GKL, Sunny R
doaj  

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