Results 1 to 10 of about 130,743 (192)

Comparison of Different Approaches for Calculating LOD and LOQ in an HPLC-Based Analysis Method [PDF]

Pharmaceutical Sciences
Background: Sensitivity in the determination of the drug concentration is critical in pharmaceutical analysis. This research investigates several approaches for determining two sensitivity parameters, the Limit of Detection (LOD) and the Limit of ...
Raha Kaviani
doaj   +2 more sources

Comparison of approaches for assessing detection and quantitation limits in bioanalytical methods using HPLC for sotalol in plasma

Scientific Reports
The limit of detection (LOD) and limit of quantification (LOQ) stand elements in the validation of analytical and bioanalytical methods as emphasized in numerous guidelines.
Lamia Zaari Lambarki, Fayssal Jhilal, Lamia Slimani, Ridouan El Hajji, Fadil Bakkali, Samy Iskandar, Mariam El Jemli, Bouchaib Ihssane, Wafaa El Ghali, Taoufiq Saffaj   +9 more
doaj   +2 more sources

Influence of Chromatographic Conditions on LOD and LOQ of Fluoxetine and Sertraline Analyzed by TLC-Densitometric Method

Processes, 2022
This research introduces the analysis of fluoxetine and sertraline by means of the TLC-densitometric method. They provide information on LOD and LOQ under various chromatographic conditions.
Wioletta Parys, Alina Pyka-Pająk
semanticscholar   +1 more source

VALIDATION OF SPECTROPHOTOMETRIC METHOD TO QUANTIFY QUERCETIN IN THE IN VITRO DISSOLUTION STUDY OF SELF NANO-EMULSIFYING DRUG DELIVERY SYSTEM (SNEDDS)

Jurnal Farmasi Sains dan Praktis, 2022
Quercetin possesses low solubility and decreases oral bioavailability. One way to increase the bioavailability of quercetin is by formulating a self-nanoemulsifying drug delivery system (SNEDDS).
Wildan Khairi Muhtadi, Ferdy Firmansyah, Tiara Tri Agustini, Pricillia Rahayu, Siti Arifah Fitriyanti, Rodhia Ulfa   +5 more
doaj   +1 more source

Simultaneous Analysis of Fenpropimorph and Fenpropimorph Acid in Six Different Livestock Products Using a Single-Sample Preparation Method Followed by Liquid Chromatography–Tandem Mass Spectrometry

Molecules, 2021
Pesticides in livestock products must be measured to ensure food safety. We developed a single-sample preparation method followed by liquid chromatography–tandem mass spectrometry (LC-MS/MS) for simultaneous determination of fenpropimorph and ...
Seon Wook Kim, Da Jung Lim, In Seon Kim
doaj   +1 more source

Clinical relevance of an objective flow cytometry approach based on limit of detection and limit of quantification for measurable residual disease assessment in acute myeloid leukemia. A post-hoc analysis of the GIMEMA AML1310 trial

Haematologica, 2022
Using a multiparametric flow cytometry assay, we assessed the predictive power of a threshold calculated applying the criteria of limit of detection (LOD) and limit of quantitation (LOQ) in adult patients with acute myeloid leukemia. This was a post-hoc
Francesco Buccisano, Raffaele Palmieri, Alfonso Piciocchi, Valentina Arena, Luca Maurillo, Maria-Ilaria Del Principe, Giovangiacinto Paterno, Maria-Antonietta Irno-Consalvo, Tiziana Ottone, Mariadomenica Divona, Consuelo Conti, Daniela Fraboni, Serena Lavorgna, William Arcese, Maria Teresa Voso, Adriano Venditti   +15 more
doaj   +1 more source

Development of Head Space Sorptive Extraction Method for the Determination of Volatile Compounds in Beer and Comparison with Stir Bar Sorptive Extraction [PDF]

, 2020
A headspace sorptive extraction method coupled with gas chromatography-mass spectrometry (HSSE-GC-MS) was developed for the determination of 37 volatile compounds in beer.
Castro Mejías, Remedios, Durán Guerrero, Enrique, García Barroso, Carmelo, Ruvalcaba, José E.   +3 more
core   +1 more source

Investigating a Simple and Sensitive High-performance Liquid Chromatography Method for Simultaneous Determination of Apigenin, Catalpol, and Gallic Acid Contents in Plantago Lanceolata L. and Plantago Major L. [PDF]

Pharmaceutical and Biomedical Research, 2023
Background and Objectives: Plantago is a diverse genus of the Plantaginaceae family. Plantago lanceolata L. (P. lanceolata) and Plantago major L. (P. major) are used commercially worldwide as a traditional treatment for many diseases. A sensitive, simple,
Samaneh Rahamouz-Haghighi, Khadijeh Bagheri, Ali Sharafi   +2 more
doaj  

Development of a High-Throughput Screening Analysis for 195 Pesticides in Raw Milk by Modified QuEChERS Sample Preparation and Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry

Separations, 2022
This study aimed to develop a simple, high-throughput method based on modified QuEChERS (quick, easy, cheap, effective, rugged, and safe) followed by liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS) for the rapid ...
Xingqiang Wu, Kaixuan Tong, Changyou Yu, Shuang Hou, Yujie Xie, Chunlin Fan, Hui Chen, Meiling Lu, Wenwen Wang   +8 more
doaj   +1 more source

Simultaneous Screening and Determination of Eleven Mycotoxins in Tomato by Ultra-high Performance Liquid Chromatography-Quadrupole/Orbitrap High-Resolution Mass Spectrometry [PDF]

Shipin Kexue, 2023
A method was developed for the simultaneous screening and determination of eleven mycotoxins in tomato by ultra-high performance liquid chromatography-quadrepole/orbitrap high-resolution mass spectrometry (UPLC-Q/Orbitrap HRMS).
WANG Changzhao, LI Zihao, ZHANG Yali, LIN Fang, LI Jianhua, ZOU Yang, YANG Yue
doaj   +1 more source