Results 11 to 20 of about 130,892 (321)
Limit of Blank (LOB), Limit of Detection (LOD), and Limit of Quantification (LOQ)
Organic & Medicinal Chemistry International Journal, 2018 For any analytical method development and validation, it is require developing arobust, accurate, precise, and linear method which is the heart for the development activities for drug product and drug substances.
Mohamad Taleuzzaman
semanticscholar +2 more sources
Are LOD and LOQ Reliable Parameters for Sensitivity Evaluation of Spectroscopic Methods? [PDF]
Journal of AOAC INTERNATIONAL, 2018 The limit of detection (LOD) and the limit of quantification (LOQ) are common parameters to assess the sensitivity of analytical methods. In this study, the LOD and LOQ of previously reported terbium sensitized analysis methods were calculated by ...
Saba Ershadi, A. Shayanfar
semanticscholar +3 more sources
Blood, 2020 Background: In Acute Myeloid Leukemia (AML), identification of measurable residual disease (MRD) thresholds with clinical significance is still a matter of debate.
R. Palmieri +16 more
semanticscholar +2 more sources
Determination of the LOQ in real-time PCR by receiver operating characteristic curve analysis: application to qPCR assays for Fusarium verticillioides and F. proliferatum [PDF]
Analytical and Bioanalytical Chemistry, 2011 Real-time PCR (qPCR) is the principal technique for the quantification of pathogen biomass in host tissue, yet no generic methods exist for the determination of the limit of quantification (LOQ) and the limit of detection (LOD) in qPCR.
Sabine Nutz +2 more
semanticscholar +4 more sources
Clinical Chemistry, 1994 Abstract The limit of detection (LOD) for any analytical procedure, the point at which analysis is just feasible, may be determined by a statistical approach based on measuring replicate blank (negative) samples or by an empirical approach, consisting of measuring progressively more dilute concentrations of analyte.
D A Armbruster, M D Tillman, L. M. Hubbs
semanticscholar +3 more sources
Structural insights into dsRNA processing by Drosophila Dicer-2–Loqs-PD
Nature, 2022 Abstract Small interfering RNAs (siRNAs) are the key components for RNA interference (RNAi), a conserved RNA-silencing mechanism in many eukaryotes 1,2 . In Drosophila , an RNase III enzyme Dicer-2 (Dcr-2), aided by its cofactor ...
Shichen Su +9 more
openaire +2 more sources
Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila [PDF]
Nature Structural & Molecular Biology, 2009 In Drosophila melanogaster, the small interfering RNA (siRNA) pathway is triggered by exogenous double-stranded RNA (dsRNA) or upon viral infection. This pathway requires Dicer-2 (Dcr-2) in association with a dsRNA-binding protein (dsRBP) called R2D2.
João Trindade, Marques +5 more
openaire +2 more sources
Faecal haemoglobin can define risk of colorectal neoplasia at surveillance colonoscopy in patients at increased risk of colorectal cancer. [PDF]
, 2020 Background: Quantitative faecal immunochemical tests measure faecal haemoglobin concentration (f-Hb), which increases in the presence of colorectal neoplasia.Objective: We examined the diagnostic accuracy of faecal immunochemical test (FIT)in patients at
Cleary, Shirley +9 more
core +2 more sources
Agriculture, 2023 This paper presents studies performed for the monitoring of imidacloprid, clothianidin and thiamethoxam residues applied as seed treatment in rapeseed (Brassica napus ssp. oleifera), maize (Zea mays) and sunflower crops (Helianthus annuus).
Roxana Zaharia +7 more
doaj +1 more source
Neonatal Feeding Trajectories in Mothers With Bipolar Disorder Taking Lithium: Pharmacokinetic Data
Frontiers in Pharmacology, 2021 Purpose: Women who take lithium during pregnancy and continue after delivery may choose to breastfeed, formula feed, or mix these options. The aim of the study was to evaluate the neonatal lithium serum concentrations based on these three feeding ...
Maria Luisa Imaz +8 more
doaj +1 more source