Lorazepam during breastfeeding: a pharmacokinetic case report and exploratory pharmacovigilance assessment – a contribution from the ConcePTION project [PDF]
Frontiers in PharmacologyIntroductionKnowledge regarding lorazepam use during breastfeeding is limited and so are quantitative data on lorazepam transfer into human milk. Lorazepam transfer to human milk was characterized in a single case and pharmacovigilance databases were ...
Ghazaleh Shitreh +23 more
doaj +2 more sources
Effects of baclofen and lorazepam on interhemispheric inhibition in humans [PDF]
Experimental PhysiologyTranscallosal projections within the corpus callosum allow for the transfer of information between bilateral primary motor cortices (M1). Interhemispheric inhibition (IHI) is one approach to probe transcallosal communication using transcranial magnetic ...
Faith C. Adams +8 more
doaj +2 more sources
Revisiting the Role of Lorazepam as an Adjunct in the Management of Chemotherapy-Induced Nausea and Vomiting: A Systematic Review and Meta-Analysis [PDF]
BiomedicinesBackground/Objectives: While standard antiemetic regimens have evolved, breakthrough symptoms and anticipatory nausea persist. Lorazepam has historically been used as an adjunct, yet a comprehensive re-evaluation of its efficacy across historical trials ...
Tzu-Rong Peng +3 more
doaj +2 more sources
Lorazepam-induced full resolution of catatonia and psychosis in Parkinson’s disease with acromegaly: a case report [PDF]
Frontiers in PsychiatryBackgroundParkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopamine-producing neurons, which results in motor issues such as tremors, stiffness, and slowness of movement. In addition to experiencing non-motor symptoms
Aasal Alnafisi +13 more
doaj +2 more sources
A Comparative Study on Intranasal Versus Intravenous Lorazepam in the Management of Acute Seizure in Children [PDF]
Folia Medica, 2021 Introduction: The acute seizure in childhood is a medical emergency which is usually managed by benzodiazepines used as a first line of therapy. There are no strict guidelines of using intranasal lorazepam in India.
Nandan Rudra +2 more
doaj +3 more sources
Baclofen Misuse in Clinical Practice: A Case Report on Management Strategies [PDF]
Clinical Case ReportsBaclofen, a GABA_B receptor agonist, is increasingly linked to misuse and severe withdrawal symptoms, including acute neuropsychiatric manifestations.
Mostafa Yousef +3 more
doaj +2 more sources
Neurochemical and behavioral effects of lorazepam: A dose related study
Pakistan Journal of Pharmaceutical Sciences, 2021 Present study was designed to monitor the dose dependent effects of lorazepam; a benzodiazepine (CNS depressant). It is the primary drug of choice for treatment of anxiety and to produce calming effects. However, repeated administration of this lorazepam
Huma Ikram +4 more
doaj +1 more source
Treatment of Agitation With Lorazepam in Clinical Practice: A Systematic Review
Frontiers in Psychiatry, 2021 Acute agitation is a frequent occurrence in both inpatient and outpatient psychiatric settings, and the use of medication to calm a patient may be warranted to mitigate the situation.
Mario Amore +3 more
doaj +1 more source
Lorazepam causing drug-induced liver injury : Rare entity
European Psychiatry, 2021 Introduction Lorazepam is a benzodiazepine derivative that is globally used for the therapy of anxiety and insomnia. Objectives The objective of our work was to show that Lorazepam can be a cause of unexpected liver injury even though it is a rare ...
S. Sellami +4 more
doaj +1 more source
Therapeutic Advances in Gastrointestinal Endoscopy, 2023 Background: Digestive endoscopy (DE) is uncomfortable for most patients. Lorazepam is a potent benzodiazepine with anxiolytic and sedative effects. Objective: This study aims to determine the sedative effect of sublingual lorazepam versus placebo as a ...
Maryam Hasanzarrini +5 more
doaj +1 more source