Results 81 to 90 of about 5,136 (294)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Tras las huellas de Don Quijote. Breves notas sobre la influencia cervantina en The Lord of the Rings / In the footsteps of Don Quijote: Brief Notes on Cervantes Influence in The Lord of the Rings

Tirant, 2016
Al contrario de lo sucedido en España, el interés por la obra de Cervantes en Inglaterra se mantiene constante desde la época de su publicación hasta el siglo XX.
Ana María Mariño Arias
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Medievalism, the Lost Book, and Handicraft in The Lord of the Rings [PDF]

, 2022
This thesis considers medievalism and the lost book in J. R. R. Tolkien’s text, The Lord of the Rings, and the effects of inventing textual history. The Lord of the Rings was chosen for this thesis as the Ur-text of fantasy and medievalism like World ...
Istvandi, Scott
core  

Lord of the Rings…

Journal of Telangana Orthopaedic Surgeons Association
The scenario of an integrated lesson for students in grades 10–11 is presented, which combines the material of chemistry, physics, literature and history courses. During the lesson, the role of rings with talisman stones in the fate and work of Alexander Pushkin is traced.
openaire   +2 more sources

Vegetal Modes of Resistance: Arboreal Eco-Rebellion in The Lord of the Rings

Humanities
This article posits that a fictional eco-rebel might be not just a human (child or young adult), but also a plant, revolting against the destruction of its dwelling place. The argument is furthered by way of a literary analysis of arboreal agency in J. R.
Lykke Guanio-Uluru
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Merveilleux et fantastique (?) dans The Lord of the Rings [PDF]

, 1979
Poyet Françoise. Merveilleux et fantastique (?) dans The Lord of the Rings. In: Caliban, n°16, 1979. Fantastique anglo-américain. pp.
Françoise Poyet, Poyet, Françoise
core   +1 more source

PROVERBIAL PLAY

Proverbium, 2014
Proverbs are a significant part of the linguistic complexity that Tolkien created for Middle Earth: both Tolkien as narrator/author and many of his characters use them.
Esther Clinton
doaj  

Fictionality in “Fog on the Barrow-downs”: Myth and Reference

Interlitteraria
Exploring fictionality as the link between imagined and referential reality, the paper draws on the theoretic al framework of cognitive narratology in examining the mechanisms on which the creation of myth relies in the narratives introduced at the ...
Sanja Ignjatović, Marija Budimski
doaj   +1 more source