Results 151 to 160 of about 1,888 (198)

Formulation and Evaluation of Proniosomes Containing Lornoxicam

open access: yesDrug Delivery and Translational Research, 2016
Proniosomes are the new generation provesicular drug delivery system of non-ionic surfactant, lecithin and cholesterol which upon reconstitution get converted into niosomes. The objective of current study was to develop stable and sustain transdermal delivery system for lornoxicam.
Jyotsana Madan, Kamal Dua
exaly   +4 more sources

Role of Human Liver Microsomal CYP2C9 in the Biotransformation of Lornoxicam

open access: yesEuropean Journal of Clinical Pharmacology, 1996
OBJECTIVE The nature of the enzyme(s) catalysing the biotransformation of lornoxicam to one of its major metabolites, 5'-hydroxy-lornoxicam, has been investigated in human liver microsomes.
T Leemann, P Dayer
exaly   +2 more sources
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Lornoxicam

2011
A comprehensive profile on lornoxicam, the oxicam nonsteroidal anti-inflammatory agent which is used in the muscular skeletal and joint disorders such as osteoarthritis and rheumatoid arthritis, is prepared. This profile contains the following sections: description, uses and applications, methods of preparation, physical characteristics, methods of ...
Mahrous O, Ahmed, Abdullah A, Al-Badr
openaire   +3 more sources

Presumptive Lornoxicam Intoxication in Four Dogs

Topics in Companion Animal Medicine, 2021
Lornoxicam is a nonsteroidal anti-inflammatory drug extensively used in human medicine, which is not approved for canine use. Lornoxicam intoxication has been rarely reported in dogs. Four dogs of various breeds, aged 7 months to 10 years, were admitted with a recent history of melena, anorexia and depression, occurring 1-4 days after the ingestion of ...
Vicky, Karakitsou   +7 more
openaire   +2 more sources

Preoperative peritonsillar lornoxicam infiltration is not superior to intravenous lornoxicam for pain relief following tonsillectomy in adults

European Journal of Anaesthesiology, 2010
Nonsteroidal anti-inflammatory drugs have peripheral analgesic effects. We compared the efficacy of peritonsillar infiltration versus intravenous (i.v.) lornoxicam on pain relief after tonsillectomy in adults.Sixty adult patients scheduled for tonsillectomy were randomly assigned into three groups in a double-blind placebo-controlled study.
Salah A, Ismail, Hany A, Mowafi
openaire   +2 more sources

Effect of the CYP2C9*3 Allele on Lornoxicam Metabolism

Clinica Chimica Acta, 2006
We investigated whether the CYP2C9 genotypes would affect lornoxicam metabolism in healthy volunteers.Twelve healthy volunteers who had been genotyped for CYP2C9 gene were selected to participate in our study. After 8 mg lornoxicam was taken, blood samples were drawn from 0 to 36 h.
Zhao-Qian Liu, Yi-Jing He, Chen-Hui Luo
exaly   +3 more sources

Clinical Pharmacokinetics of Lornoxicam

Clinical Pharmacokinetics, 1998
Lornoxican (chlorotenoxicam) is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class. Unlike other oxicams, lornoxicam has a relatively short plasma half-life (3 to 5 hours). Lornoxicam is eliminated following biotransformation to 5'-hydroxy-lornoxicam, which does not undergo enterohepatic recirculation.
N M, Skjodt, N M, Davies
openaire   +2 more sources

Organotin‐Drug Interactions. Organotin Adducts of Lornoxicam, Synthesis and Characterisation of the First Complexes of Lornoxicam

European Journal of Inorganic Chemistry, 2003
AbstractThe synthesis and spectral characterisation of novel organotin complexes [SnMe2(lorn)] (1) and [SnBu2(lorn)] (2) of the potent and widely used anti‐inflammatory drug lornoxicam, H2lorn, are reported. Crystal structure determinations of complexes1 and 2 showed that the ligand is doubly deprotonated at the oxygen and amide nitrogen atoms and is ...
Angeliki Galani   +3 more
openaire   +1 more source

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