Pharmacogenomic Calling From Whole-Exome Sequencing in the Taiwanese Population-A Real-World Experience. [PDF]
This study evaluated pharmacogenomic (PGx) calling from whole‐exome sequencing (WES) in 3562 Taiwanese individuals. Fourteen pharmacogenes were reliably identified, with each person carrying an average of ~2.4 actionable phenotypes. The high actionable frequencies of G6PD deficiency and HLA‐B*58:01 highlight ethnic differences and support WES as a ...
Lin HH +9 more
europepmc +2 more sources
INTRODUCTION: Nonsteroidal anti-inflammatory drugs have become a popular part of multimodal analgesic regimens particularly in ambulatory surgery. This study was designed to search the efficacy of preoperative administration of lornoxicam or paracetamol ...
Alp Alptekin +5 more
doaj +1 more source
Questionable role of opioids for analgesia in renal colic and its urological interventions. [PDF]
Abstract Objectives To review the different analgesic modalities and benefits of non‐opioid pain management options as well as their evidence‐based, established superiority, compared to opioid medications. Materials We review the updated literature about pain management of renal colic, a prevalent and painful urologic condition.
Krieger A +4 more
europepmc +2 more sources
Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach
The present study aims to design and optimize the lornoxicam dispersible tablet (LXDT) formulation using the Quality by design (QbD) approach. A randomized Box–Behnken experimental design was used to characterize the effect of the critical factors, such ...
Nawaf Almotairi +3 more
doaj +1 more source
Correlation between serum concentrations of homocysteine, folate and vitamin B12 in patients with schizophrenia [PDF]
Introduction: The role of hyperhomocysteinemia in psychotic disorder can be explained by partial antagonism of homocysteine on NMDA-glycine receptor. Plasma concentration of homocysteine is an indicatorof the status of the B-vitamins (folate, B12, B6 ...
Fisekovic, Saida +5 more
core +3 more sources
The synergistic antinociceptive effect of lornoxicam in combination with tramadol
Introduction: One of the most important priorities in therapy is pain control. Therefore, many different groups of drugs are being used for this purpose, primarily opioid analgesics and non-steroidal anti-inflammatory drugs (NSAIDs).
Amela Saračević, Fahir Bečić
doaj +1 more source
Attenuation of hemodynamic responses to laryngoscopy and tracheal intubation: Propacetamol versus lidocaine - A randomized clinical trial [PDF]
The purpose of this study is to assess the effects of propacetamol on attenuating hemodynamic responses subsequent laryngoscopy and tracheal intubation compared to lidocaine.
Darabi, H. +11 more
core +4 more sources
Comparison of Lornoxicam and Fentanyl when added to Lidocaine in Intravenous Regional Anesthesia
Background and objectives: In this study, our goal was to compare intraoperative and postoperative analgesic effects of lornoxicam and fentanyl when added to lidocaine Intravenous Regional Anesthesia (IVRA) in a group of outpatients who underwent hand ...
Nezih Sertoz +2 more
doaj +1 more source
Abstract Objective This study was designed to evaluate the postoperative efficacy and safety of using an ibuprofen gargle as a pain management strategy for patients who have undergone mandibular third molar extraction. We also ensured that the quality of treatment was not compromised throughout the study.
Takeshi Ioroi +7 more
wiley +1 more source
Comparação de lornoxicam e fentanil adicionados à lidocaína em anestesia regional intravenosa
JUSTIFICATIVA E OBJETIVO: Comparar os efeitos analgésicos nos períodos intra e pós-operatório de lornoxicam e fentanil adicionados à lidocaína para anestesia regional intravenosa (ARIV) em um grupo de pacientes submetidos à cirurgia de mão.
Nezih Sertoz +2 more
doaj +1 more source

