Piroxicam accelerates diabetic foot ulcer healing via ERα-dependent mitochondrial protection and oxidative stress relief [PDF]
IntroductionThe pathology of diabetic foot ulcer (DFU) is characterized by keratinocyte dysfunction, non-resolving inflammation, and oxidative stress.
Qing-Qing Liao +9 more
doaj +2 more sources
The protective effects of garlic (Allium sativum var. Solo Garlic) extract mitigates piroxicam-induced liver damage and oxidative stress in rats [PDF]
Background: Piroxicam, a nonsteroidal antiinflammatory drug, is commonly used to induce inflammation in experimental models of inflammatory bowel disease (IBD).
Maya Nurwartanti Yunita +10 more
doaj +2 more sources
Self-nanoemulsifying drug delivery system (SNEDDS) of piroxicam: evaluation on anti-inflammantory activity in wistar rats [PDF]
Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used for arthritis, gout, and other musculoskeletal disorders. Piroxicam is poorly soluble in water and according to the biopharmaceutical drug classification system (BCS) is ...
Yudha Rizky Nuari +2 more
doaj +1 more source
Purpose: In this study, a controlled release drug delivery system loaded with piroxicam and methadone was synthesized and used subcutaneously in rat with experimental tibial defect and healing were assessed histopathologically. Materials and Methods:
Pegah Khosravian +5 more
doaj +1 more source
Photostability of piroxicam in the inclusion complex with 2-hydroxypropyl-β-cyclodextrin [PDF]
The aim of this work is the protection of piroxicam from photodegradation by forming inclusion complex with 2-hydroxypropyl-β-cyclodextrin. Piroxicam:2-hydroxypropyl-β-cyclodextrin molecular inclusion complex was prepared by coprecipitation ...
Nikolić Vesna D. +6 more
doaj +1 more source
Piroxicam belongs to BCS class II and has low solubility. Self-nanoemulsifying drug delivery systems (SNEDDS) are considered a potential approach for increasing the solubility and release of piroxicam.
Septiawan Adi Nugroho +2 more
doaj +1 more source
Effect of natural polymers on the physicochemical properties and ulcerogenic activity of piroxicam [PDF]
Piroxicam belongs to the class of acidic non-steroidal antiinflammatory drugs. Under the acidic conditions in which its absorption takes place, its low soly. and dissoln. rate has been well documented.
T. El-Faham, M. Mahmoud, M. Hassan
doaj +1 more source
Reducing ulcerogenic effect of self-nano emulsifying drug delivery system of piroxicam [PDF]
Piroxicam is antiinflammatory non-steroidal (AINS) drug group that has anti-inflammatory, analgesic and antipyretic effects. Like most other AINS drugs, piroxicam has low solubility and has gastrointestinal (ulcerogenic) side effects on long-term use ...
Iis Wahyuningsih +2 more
doaj +1 more source
Pharmaceutical Cocrystal of Piroxicam: Design, Formulation and Evaluation [PDF]
Purpose: Cocrystallisation of drug with coformers is a promising approach to alter the solid sate properties of drug substances like solubility and dissolution.
Prabhakar Panzade +3 more
doaj +1 more source
Electrocatalytic performance of Au@Cu Nanoparticle Chains as Sensor for Determination of Piroxicam
A chemical reduction technique at low temperature was employed to synthesize Au and Cu nanoparticle chains (Au@Cu NCs) with sodium citrate as the growth reducing agent, stabilizer and structure directing agent, chloroauric acid (HAuCl4) and copper ...
Na Wu +6 more
doaj +1 more source

