Results 11 to 20 of about 9,407 (166)

Dermatological Adverse Events Associated With Lapatinib Treatment in Dogs With Urothelial Carcinoma: A Retrospective Study. [PDF]

open access: yesVet Dermatol
Lapatinib is widely used in human oncology; however, dermatological adverse events (DAEs) are common and have been correlated with treatment efficacy. In veterinary medicine, lapatinib use in combination with piroxicam has been shown to be effective in treating canine urothelial carcinoma (UC); however, the incidence and prognostic significance of DAEs
Horita K, Yonezawa T, Momoi Y, Maeda S.
europepmc   +2 more sources

Polymorphism in Piroxicam

open access: yes, 2016
Piroxciam is a polymorphic drug. However, reports on the number and nomenclature of the polymorphs of piroxicam and the complete hydrogen-bonding patterns of piroxicam molecules in the crystal forms are in conflict and are sources of confusion, which we ...
Francis X. Muller (2703424)   +3 more
core   +5 more sources

Pharmacokinetic Studies with Piroxicam [PDF]

open access: yes, 1991
When one examines the scientific literature pertaining to the NANSAID, piroxicam, it is clear that controversy of one type or another has not been far away.
Milligan, Peter A
core   +6 more sources

Pharmacological Influences on the R2 Blink Reflex Response in Healthy Participants: A Systematic Review. [PDF]

open access: yesEur J Neurosci
Pharmacological modulation of the R2 blink reflex was comparable whether responses were elicited using standard patch or concentric electrodes. Across nine studies, noradrenergic and GABAergic interventions produced the most consistent effects, supporting the R2 blink reflex as a sensitive biomarker of trigeminofacial nociceptive processing.
Murphy J   +5 more
europepmc   +2 more sources

The Development of Transdermal Piroxicam Using HPMC Matrices With PVP K-30 as a Penetration Enhancer [PDF]

open access: yes, 2006
The physicochemical properties such as solubility, partition coefficient, and membrane permeability of a drug are required for formulating and estimating drugs absorption that pass through biological membranes.
Aryani, Ni Luh Dewi
core   +2 more sources

Pengaruh Pemberian Ekstrak Jintan Hitam (Nigella sativa) terhadap Kadar MDA dan SOD Hepar Tikus (Rattus norvegicus) yang Diinduksi Piroxicam

open access: yesJurnal Fisika Flux, 2021
Piroxicam merupakan salah satu obat anti inflamasi non steroid (OAINS) yang berpotensi menyebabkan kerusakan sel pada organ hepar. Kerusakan hepar ditandai dengan tingginya kadar MDA (Malondialdehyde) dalam darah.
Septiana Kurniasari
doaj   +1 more source

Apoptosis induced by piroxicam plus cisplatin combined treatment is triggered by p21 in mesothelioma. [PDF]

open access: yesPLoS ONE, 2011
BackgroundMalignant mesothelioma (MM) is a rare, highly aggressive tumor, associated to asbestos exposure. To date no chemotherapy regimen for MM has proven to be definitively curative, and new therapies for MM treatment need to be developed.
Alfonso Baldi   +12 more
doaj   +1 more source

Formulation and evaluation of topical piroxicam microemulgel for arthritis

open access: yesJournal of Contemporary Pharmacy, 2023
Background: Piroxicam is an anti-inflammatory, analgesic, and antipyretic drug. Piroxicam is widely used in the management of chronic pain. The objective of this work was to develop and analyze topical Piroxicam microemulgel to improve drug solubility ...
Mehreen Sattar   +5 more
doaj   +1 more source

Protective potential of piroxicam on human peripheral blood mononuclear cells against the suppressive capacity of glioblastoma cell lines

open access: yesScientific Reports, 2022
Dexamethasone, a common medication used in the treatment regimen of glioblastoma, has broad inhibitory effects on the immune responses. Here, in an in vitro study, we examined the effects of piroxicam, a potent substitute for dexamethasone, on peripheral
Jahangir Abdesheikhi   +5 more
doaj   +1 more source

ENHANCEMENT OF THE DISSOLUTION RATE AND BIOAVAILABILITY OF PIROXICAM FROM HARD GELATIN CAPSULES AND DIRECT COMPRESSED DISPERSIBLE TABLETS VIA SURFACE HYDROPHILIZATION

open access: yesZagazig Journal of Pharmaceutical Sciences, 2000
The dissolution rate of piroxicam, a nonsteroidal anti-inflammatory drug (NSAID) was markedly increased by the surface hydrophilization technique using Tween 80, polyvinylpyrrolidine K-30 (PVP) and polyethylene glycol 4000 (PEG). The in- vitro release of
Fergany Mohammed
doaj   +1 more source

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