Results 21 to 30 of about 6,072 (168)

Hypertrophic Osteopathy Associated With Primary Pulmonary Histiocytic Sarcoma in a Dog. [PDF]

Vet Med Sci
ABSTRACT Hypertrophic osteopathy (HO) is a paraneoplastic or parainflammatory syndrome characterised by painful periosteal new bone formation and soft tissue swelling, most commonly associated with thoracic neoplasia. The pathogenesis of HO remains incompletely understood and may involve neurovascular mechanisms, altered pulmonary filtration of ...
Rinaldi V, Ridolfi F, Finotello R, Rosto M, Luciani A, Boari A, Crisi PE.   +6 more
europepmc   +2 more sources

Synthesis and biological evaluation of Piroxicam derivative as a lead chelator

Main Group Metal Chemistry, 2019
Lead as a potent environmental and occupational pollutant, exerts its toxic effect mainly through oxidative stress induction. Currently, chelation therapy is the only medical management of metal intoxications in clinic, but its administration is ...
Hosseini Sayed Masoud, Imani Ali, Rahimzadegan Milad, Mohammadi Saeid, Golaghaei Alireza   +4 more
doaj   +1 more source

Piroxicam-mediated modulatory action of 5-hydroxytryptamine serves as a "brake" on neuronal excitability in ischemic stroke

Neural Regeneration Research, 2015
Our previous studies indicated an increase in extracellular γ-aminobutyric acid (GABA) in rodent′s ischemic brain after Piroxicam administration, leading to alleviation of glutamate mediated excitotoxicity through activation of type A GABA receptor ...
Pallab Bhattacharya, Anand Kumar Pandey, Sudip Paul, Ranjana Patnaik   +3 more
doaj   +1 more source

Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids

Pharmaceutics, 2010
Several biologically relevant phospholipids were assessed as potential carriers/additives for rapidly dissolving solid formulations of piroxicam (Biopharmaceutics Classification System Class II drug).
Muhammad D. Hussain, Inna Miroshnyk, James F. Brausch, Muhammad J. Habib, Sabiruddin Mirza   +4 more
doaj   +1 more source

FORMULATION AND PHYSICOCHEMICAL CHARACTERIZATION OF PIROXICAM CONTAINING POLYMER FILMS [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2010
Piroxicam is a potent nonsteroidal anti-inflammatory drug associated with many side effects when taken orally. An attention was paid in this work to formulate and characterize piroxicam containing polymer films for dermal use.
Sayed H. Auda, Mahmoud M. Ahmed, S. Abd El-Rasoul, K. I. Saleh   +3 more
doaj   +1 more source

Fabrication of Sensitive Voltammetric Sensors and Microsensors for Piroxicam by Modifying Nafion and MWCNTs Composite Film on the Electrode Surface

Electrochemistry
Piroxicam is a common painkiller and anti-inflammatory drug. Precise monitoring of piroxicam levels can mitigate side effects, but current methods are often slow and complicated. An easily fabricated and highly sensitive voltammetric sensor for piroxicam
Jin LI, Siyuan HAN, Yue CUI, Tong XING, Tingting ZHENG, Jing YANG, Yu FU, Jie LIAN, Fangyuan ZHAO, Weining ZHAO   +9 more
doaj   +1 more source

Biomedical Applications of Thermosensitive Hydrogels for Controlled/Modulated Piroxicam Delivery

Gels, 2023
The objectives of this study are the synthesis of thermosensitive poly(N-isopropylacrylamide-co-2-hydroxypropyl methacrylate), p(NiPAm-HPMet), hydrogels and the analysis of a drug-delivery system based on piroxicam, as a model drug, and synthesized ...
Snežana Ilić-Stojanović, Ljubiša Nikolić, Vesna Nikolić, Ivan Ristić, Suzana Cakić, Slobodan D. Petrović   +5 more
doaj   +1 more source

Protection Effect of Self-Nanoemulsifying Drug Delivery System (SNEDDS) Piroxicam as Ulcerogenic Agent towards Malondialdehid Level and Protein Expression of Caspase-3, COX-1, COX-2 at Rat Gastric

Journal of Food and Pharmaceutical Sciences, 2020
The aim of this study was to determine the protection effect of SNEDDS piroxicam ulcerogenic agent against malondialdehyde (MDA) level and protein expression of caspase-3, COX-1, COX-2. The research was conducted using the test animals as much as 30 male
Iis Wahyuningsih, Kurnia Ambarwati, Erninda Ayu Hapsari, Afifah Fauziyyah, Azis Ikhsanudin, Deasy Vanda Pertiwi, Wahyu Widyaningsih   +6 more
doaj   +1 more source

PREPARATION AND EVALUATION OF PIROXICAM - PLURONIC SOLID DISPERSIONS [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2003
With an objective of enhancing the dissolution rate of piroxicam (PXM), solid dispersions(SDs) of piroxicam were prepared using different grades of pluronic F-68 (Pl. F-68), pluronicF-98 (Pl. F-98), and pluronic F-127 (Pl.
M. El-Badry, M. Fathy
doaj   +1 more source

Piroxicam-β-cyclodextrin: a GI safer piroxicam.

Current medicinal chemistry, 2013
Although NSAIDs are very effective drugs, their use is associated with a broad spectrum of adverse reactions in the liver, kidney, cardiovascular (CV) system, skin and gut. Gastrointestinal (GI) side effects are the most common and constitute a wide clinical spectrum ranging from dyspepsia, heartburn and abdominal discomfort to more serious events such
openaire   +2 more sources