Results 21 to 30 of about 9,407 (166)

Protective effect of antioxidant rich aqueous curry leaf (Murraya koenigii) extract against gastro-toxic effects of piroxicam in male Wistar rats

open access: yesToxicology Reports, 2014
Piroxicam (chemically 4-hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide), a classical non-steroidal anti-inflammatory drug (NSAID) is orally administered to arthritic patients.
Syed Benazir Firdaus   +13 more
doaj   +1 more source

Comparison of Analgesic Effect of Rosmarinic Acid With Piroxicam in Mice [PDF]

open access: yesInternational Journal of Basic Science in Medicine, 2022
Introduction: Nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the most widely used drugs in the treatment of pain and inflammation. Although, their side effects i.e.; gastrointestinal and renal adverse effects, limit the use of these drugs ...
Mohsen Moradi   +6 more
doaj   +1 more source

Comparison of Efficacy and Safety of Intramuscular Piroxicam and Tramadol for Post-operative Pain in Patients Undergoing Caesarean Delivery [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: Post-caesarean section pain can be both stressful and unfavourable. Effective and rapid reduction of pain facilitates early ambulation and care of the new born.
Tejashree Thippeswamy   +3 more
doaj   +1 more source

Cocrystals of Piroxicam with Carboxylic Acids

open access: yes, 2016
A crystal engineering method was used to investigate cocrystal formation of piroxicam with pharmaceutically acceptable carboxylic acids. Forming cocrystals of piroxicam can potentially result in solid forms with increased bioavailability.
Scott L. Childs (1333299)   +1 more
core   +2 more sources

Synthesis and biological evaluation of Piroxicam derivative as a lead chelator

open access: yesMain Group Metal Chemistry, 2019
Lead as a potent environmental and occupational pollutant, exerts its toxic effect mainly through oxidative stress induction. Currently, chelation therapy is the only medical management of metal intoxications in clinic, but its administration is ...
Hosseini Sayed Masoud   +4 more
doaj   +1 more source

Piroxicam-mediated modulatory action of 5-hydroxytryptamine serves as a "brake" on neuronal excitability in ischemic stroke

open access: yesNeural Regeneration Research, 2015
Our previous studies indicated an increase in extracellular γ-aminobutyric acid (GABA) in rodent′s ischemic brain after Piroxicam administration, leading to alleviation of glutamate mediated excitotoxicity through activation of type A GABA receptor ...
Pallab Bhattacharya   +3 more
doaj   +1 more source

Enhanced Dissolution and Oral Bioavailability of Piroxicam Formulations: Modulating Effect of Phospholipids

open access: yesPharmaceutics, 2010
Several biologically relevant phospholipids were assessed as potential carriers/additives for rapidly dissolving solid formulations of piroxicam (Biopharmaceutics Classification System Class II drug).
Muhammad D. Hussain   +4 more
doaj   +1 more source

FORMULATION AND PHYSICOCHEMICAL CHARACTERIZATION OF PIROXICAM CONTAINING POLYMER FILMS [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2010
Piroxicam is a potent nonsteroidal anti-inflammatory drug associated with many side effects when taken orally. An attention was paid in this work to formulate and characterize piroxicam containing polymer films for dermal use.
Sayed H. Auda   +3 more
doaj   +1 more source

Biomedical Applications of Thermosensitive Hydrogels for Controlled/Modulated Piroxicam Delivery

open access: yesGels, 2023
The objectives of this study are the synthesis of thermosensitive poly(N-isopropylacrylamide-co-2-hydroxypropyl methacrylate), p(NiPAm-HPMet), hydrogels and the analysis of a drug-delivery system based on piroxicam, as a model drug, and synthesized ...
Snežana Ilić-Stojanović   +5 more
doaj   +1 more source

Atividade ulcerogênica do celecoxibe, piroxicam e piroxicam associado a sulfato de zinco em modelo de granuloma em ratos [PDF]

open access: yes, 2010
OBJETIVOS: Objetivou-se neste estudo, avaliar a atividade ulcerogênica do celecoxibe (seletivo para COX-2), do piroxicam e piroxicam+sulfato de zinco (AINEs não seletivos).
Fabiana Gatti De Menezes   +3 more
core   +3 more sources

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