Results 11 to 20 of about 4,656 (255)

Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach

Pharmaceuticals, 2022
The present study aims to design and optimize the lornoxicam dispersible tablet (LXDT) formulation using the Quality by design (QbD) approach. A randomized Box–Behnken experimental design was used to characterize the effect of the critical factors, such ...
Nawaf Almotairi, Gamal M. Mahrous, Saleh Al-suwayeh, Mohsin Kazi   +3 more
doaj   +2 more sources

Development and Characterization of Lornoxicam-Infused Ocular Gel for Effective Treatment of Ocular Inflammation in Domestic Cats

The Iraqi Journal of Veterinary Medicine
Lornoxicam (LOX) is a non-steroidal anti-inflammatory drug (NSAID) effective in managing ocular inflammation. Traditional delivery methods like liquid drops are cleared rapidly and may not provide sustained therapeutic levels, necessitating the ...
Riyam S Jafer, Hanan J Kassab
doaj   +2 more sources

Formulation and characterization of lornoxicam-loaded cellulosic-microsponge gel for possible applications in arthritis

Saudi Pharmaceutical Journal, 2020
Rheumatoid arthritis (RA) is an autoimmune disease associated with severe joint pain. Herein, we report lornoxicam loaded cellulosic microsponge gel formulation with sustained anti-inflammatory effects that are required to manage arthritic pain.
Yeteng He, Khadija Majid, Maimoona Maqbool, Talib Hussain, Abid Mehmood Yousaf, Ikram Ullah Khan, Yasir Mehmood, Ambreen Aleem, Muhammad Sohail Arshad, Adnan Younus, Jorabar Singh Nirwan, Muhammad Usman Ghori, Syed A.A. Rizvi, Yasser Shahzad   +13 more
doaj   +2 more sources

Postoperative Pain Management After Lumbar Discectomy. A Systematic Review With Meta-Analyses and Trial Sequential Analyses. [PDF]

Eur J Pain
ABSTRACT Background Inadequate postoperative pain management after lumbar discectomy may delay recovery, increase the risk of chronic pain, and prolong hospitalization. Effective analgesic strategies must balance pain control with minimal adverse effects.
Zachodnik J, Bech-Azeddine R, Sandberg M, Scherwin R, Hartvigsen Grønholm Jepsen RM, Jørgensen LM, Thybo KH, Geisler A.   +7 more
europepmc   +2 more sources

Efficacy of Lornoxicam as a Pre-emptive Analgesic in Mandibular Third Molar Surgery - A Comparative Study. [PDF]

Ann Maxillofac Surg, 2023
Introduction: The most common complication following third molar surgery is pain. The purpose of the study is to determine the efficacy of lornoxicam as a preventive analgesic in patients undergoing surgical removal of impacted mandibular third molars ...
Kaila V, Bonthu V, Moturi K, Raju US, Lakshmi PDN, Budumuru A.   +5 more
europepmc   +2 more sources

Evaluation of analgetic properties of etoricoxib and lornoxicam and their effect on central sensitization in chronic low back pain

Bolʹ, Sustavy, Pozvonočnik, 2022
Introduction. Chronic low back pain is a serious health problem in the world. The phenomena of peripheral and central sensitization play an important role in the transition of acute pain to chronic, as well as in the maintenance of chronic pain.
V.I. Romanenko
doaj   +1 more source

Optimizing lornoxicam-loaded poly(lactic-co-glycolic acid) and (polyethylene glycol) nanoparticles for transdermal delivery: <i>ex vivo</i>/<i>in vivo</i> inflammation evaluation. [PDF]

Nanomedicine (Lond)
Aim: This study focused on developing a topical gel incorporating lornoxicam-loaded poly(lactic-co-glycolic acid) and polyethylene glycol (PLGA-PEG) blend nanoparticles to mitigate gastrointestinal (GIT) side effects and enhance therapeutic efficacy ...
Qaiser R, Pervaiz F, Noreen S, Hanan H, Shoukat H, Mahmood H, Ashraf MA.   +6 more
europepmc   +2 more sources

Can the preemptive use of lornoxicam or paracetamol prevent pain after inguinal hernia repair? A randomized prospective double-blind placebo controlled trial

International Journal of Abdominal Wall and Hernia Surgery, 2022
INTRODUCTION: Nonsteroidal anti-inflammatory drugs have become a popular part of multimodal analgesic regimens particularly in ambulatory surgery. This study was designed to search the efficacy of preoperative administration of lornoxicam or paracetamol ...
Alp Alptekin, Zafer Ergul, M Ercan Sonmez, Celil Ugurlu, Haluk Gumus, Hakan Kulacoglu   +5 more
doaj   +1 more source

The synergistic antinociceptive effect of lornoxicam in combination with tramadol

Journal of Health Sciences, 2013
Introduction: One of the most important priorities in therapy is pain control. Therefore, many different groups of drugs are being used for this purpose, primarily opioid analgesics and non-steroidal anti-inflammatory drugs (NSAIDs).
Amela Saračević, Fahir Bečić
doaj   +1 more source

Correlation between serum concentrations of homocysteine, folate and vitamin B12 in patients with schizophrenia [PDF]

, 2013
Introduction: The role of hyperhomocysteinemia in psychotic disorder can be explained by partial antagonism of homocysteine on NMDA-glycine receptor. Plasma concentration of homocysteine is an indicatorof the status of the B-vitamins (folate, B12, B6 ...
Fisekovic, Saida, Kucukalic, Abdulah, Memic, Amra, Sahbegovic, Sabina, Serdarevic, Nafija, Serdarevic, Raif   +5 more
core   +3 more sources