Results 31 to 40 of about 6,352,796 (319)

A protocol for a systematic review of clinical practice guidelines for recurrent miscarriage [version 2; peer review: 2 approved, 2 approved with reservations]

HRB Open Research, 2020
Recurrent miscarriage (RM) was recently re-defined by the European Society of Human Reproduction and Embryology (ESHRE) as the loss of two or more consecutive pregnancies.
Marita Hennessy, Rebecca Dennehy, Sarah Meaney, Declan Devane, Keelin O'Donoghue   +4 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Supporting those bereaved by cancer: a service evaluation and investigation of cognitive behavioural mechanisms in the treatment of prolonged grief

European Journal of Psychotraumatology
Background: Individuals bereaved by cancer face significant emotional challenges, often experiencing prolonged grief disorder (PGD), PTSD, depression, and anxiety. Effective interventions are needed to target these mental health problems.
Kirsten V. Smith, Graham R. Thew, Sarah C. Carr, Paris R. Congrave, Susie Rudge, Erin H. Thompson   +5 more
doaj   +1 more source

Parents and clinicians: partners in perinatal bereavement research –experiences from the International Stillbirth Alliance Conference 2017

Research Involvement and Engagement, 2019
In recent years, there has been a global call to reduce the numbers of preventable stillbirths and increase public awareness about the incidence and impact of pregnancy loss. The lived experiences of bereaved parents have much to contribute to developing
Rachel Rice, Daniel Nuzum, Orla O’Connell, Keelin O’Donoghue   +3 more
doaj   +1 more source

Loss Functions for Loss Estimation

The Annals of Statistics, 1988
Let X be a random variable with distribution \(P_{\theta}\), where \(\theta\in \Theta\), and d(X) a decision for \(\theta\) with loss W(\(\theta\),d(X)). A class of loss functions combining the decision error W(\(\theta\),d(X)) and the error in estimating W(\(\theta\),d(X)) by h(X) is introduced. Under these loss functions the Bayes procedure \((d_ B(X)
openaire   +3 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Effects of First Metatarsophalangeal Osteoarthritis on Plantar Pressures Across Multiple Activities

Journal of Foot and Ankle Research
Background The first metatarsophalangeal joint (MTPJ1) is one of the sites most often affected by osteoarthritis (OA). The condition contributes to activity restrictions and reduced quality of life along with biomechanical changes that affect the joint ...
Scott Telfer, Corey Wukelic, Nicholas Entress, William R. Ledoux   +3 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

“ad explorandum nova utilia et necessaria”: la raccolta e il ruolo delle nova a Bologna (secoli XIII e XIV)

, 2023
The paper focuses on the relationship of the Bolognese government with information in the late thirteenth and early fourteenth centuries. By analysing a series of unedited documents preserved in the State Archive of Bologna, the article highlights how ...
Edward Loss
core  

Auditory genotype-phenotype correlation of patients with variants in STRC

Scientific Reports
Pathogenic variants in the STRC gene are among the most common causes of autosomal recessive non-syndromic hearing loss, particularly in cases with mild-to-moderate sensorineural hearing loss (SNHL).
Tae Uk Cheon, Sun Young Joo, Sung Huhn Kim, Jae Young Choi, Dongju Won, Heon Yung Gee, Jinsei Jung   +6 more
doaj   +1 more source