Results 31 to 40 of about 4,711,390 (215)

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Strategies to Manage Obesity: Lifestyle

Methodist DeBakey Cardiovascular Journal
The treatment of obesity and cardiovascular disease (CVD) is complex, and a variety of strategies are effective in the lifestyle interventions associated with these disease states.
Ramiro Saavedra, Betsy Ramirez, Brandon Jay   +2 more
doaj   +1 more source

Bariatric surgery versus medical treatment in mildly obese patients with type 2 diabetes mellitus in Japan: Propensity score‐matched analysis on real‐world data

Journal of Diabetes Investigation, 2022
Aims/Introduction To compare glycemic control 1 year after treatment in patients with mildly obese (body mass index 27.5–34.9 kg/m2) type 2 diabetes mellitus who underwent bariatric surgery (BS) to those who received medical treatment (MT) in Japan ...
Yosuke Seki, Kazunori Kasama, Renzo Yokoyama, Akihiro Maki, Hideharu Shimizu, Hyejin Park, Yoshimochi Kurokawa   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Predictors of short-term outcomes related to central subfield foveal thickness after intravitreal bevacizumab for macular edema due to central retinal vein occlusion [PDF]

International Journal of Ophthalmology, 2016
AIM: To investigate the predictive factors for short-term effects of intravitreal bevacizumab injections on central subfield foveal thickness (CSFT) in patients with macular edema (ME) secondary to central retinal vein occlusion (CRVO).
Mei-Zi Wang, Kang Feng, Yao Lu, Fang Qian, Xin-Rong Lu, Si-Wen Zang, Lin Zhao   +6 more
doaj   +1 more source

Co-transduction of dual-adeno-associated virus vectors in the neonatal and adult mouse utricles

Frontiers in Molecular Neuroscience, 2022
Adeno-associated virus (AAV)-mediated gene transfer is an efficient method of gene over-expression in the vestibular end organs. However, AAV has limited usefulness for delivering a large gene, or multiple genes, due to its small packaging capacity (<
Zhong-Rui Chen, Zhong-Rui Chen, Jing-Ying Guo, Jing-Ying Guo, Lu He, Lu He, Shan Liu, Shan Liu, Jun-Yi Xu, Jun-Yi Xu, Zi-Jing Yang, Zi-Jing Yang, Wei Su, Wei Su, Ke Liu, Ke Liu, Shu-Sheng Gong, Shu-Sheng Gong, Guo-Peng Wang, Guo-Peng Wang   +19 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Cochlear resident macrophage mediates development of ribbon synapses via CX3CR1/CX3CL1 axis

Frontiers in Molecular Neuroscience, 2022
Cochlear ribbon synapses formed between spiral ganglion neurons and inner hair cells in postnatal mice must undergo significant morphological and functional development to reach auditory maturation.
Xinyu Song, Xinyu Song, Yang Li, Yang Li, Rui Guo, Rui Guo, Qianru Yu, Qianru Yu, Shan Liu, Shan Liu, Qi Teng, Qi Teng, Zhong-Rui Chen, Zhong-Rui Chen, Jing Xie, Jing Xie, Shusheng Gong, Shusheng Gong, Ke Liu, Ke Liu   +19 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source