Results 51 to 60 of about 4,711,390 (215)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Endoscopic removal of a weight-loss device with stoma closure using a tack-and-suture device

open access: yesVideoGIE, 2023
Areebah Waseem, BS   +5 more
doaj   +1 more source

AMPDECIDE amputation level patient decision aids: a feasibility study

open access: yesBMC Medical Informatics and Decision Making
Objective This was a feasibility study of the AMPDECIDE amputation level selection patient decision aids (one transmetatarsal vs. transtibial, the other transtibial vs. transfemoral) designed to inform a larger efficacy trial.
Alison W. Henderson   +6 more
doaj   +1 more source

Pregnancy and infant loss: a survey of families’ experiences in Ontario Canada

open access: yesBMC Pregnancy and Childbirth, 2019
Background Pregnancy and infant loss has a pervasive impact on families, health systems, and communities. During and after loss, compassionate, individualized, and skilled support from professionals and organizations is important, but often lacking ...
Jo Watson   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Recurrent Miscarriage and Infertility Services and Supports: A Qualitative Study of Views and Experiences in the Republic of Ireland

open access: yesHealth Expectations
Background Recurrent miscarriage (RM) and infertility are separately associated with psychological distress and adverse pregnancy outcomes. The dual experience is devastating for women/couples but is not considered in clinical guidance for RM or ...
Laura Aoife Linehan   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Views of knowledge users on recurrent miscarriage services and supports in the Republic of Ireland: a qualitative interview study

open access: yesBMJ Open
Objectives Women and men/partners who experience miscarriage often report poor care experiences within health services around the time of miscarriage and beyond; less is known about recurrent miscarriage (RM) care.
Karen Matvienko-Sikar   +6 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Intrapartum fetal deaths and unexpected neonatal deaths in the Republic of Ireland: 2011 – 2014; a descriptive study

open access: yesBMC Pregnancy and Childbirth, 2018
Background Intrapartum fetal death, the death of a fetus during labour, is a tragic outcome of pregnancy. The intrapartum death rate of a country is reflective of the care received by mothers and babies in labour and it is through analysing these cases ...
K. McNamara   +2 more
doaj   +1 more source

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