Results 211 to 220 of about 8,997,648 (253)

Precision Diagnostics in Age-Related Hearing Loss: Emerging Molecular Biomarkers for Early Detection and Targeted Prevention. [PDF]

Int J Gen Med
Xia Z, Lin C, Wu Y, Liu H, Wu L, Shen Z.
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Modelling risk factors for depressive symptoms in seizure disorders. [PDF]

Ther Adv Neurol Disord
Perkins JD, Mesraoua B, Alrabi A, Kamran S, Melikyan G, Imam YZ, El Sheikh L, Ali M, Babu B, Abdelmoneim MS, Elalamy O, Al Hail HJ.   +11 more
europepmc   +1 more source

Loss factor estimation of the plywood materials

, 2016
Lepšík Petr, Petřík Jan
core  

Atribuições e restrições das embaixadas nos estatutos comunais de Verona, Milão e Bolonha dos séculos XIII e XIV: apontamentos

, 2013
edward loss
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Association between presbycusis and cognitive function: contributing factors in older adult. [PDF]

Front Mol Neurosci
Wei D, Chen Y, Liu B, Tan Z.
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Clinical characteristics of asymmetric hearing loss in children from a large pediatric cohort. [PDF]

Commun Med (Lond)
Hahn LE, Fleischer M, Wohlfarth F, Althaus J, Mürbe D, Männel C, Hirschfelder A.   +6 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source