Results 121 to 130 of about 3,028,772 (307)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Deep beamforming for speech enhancement and speaker localization with an array response-aware loss function

open access: yesFrontiers in Signal Processing
Recent research advances in deep neural network (DNN)-based beamformers have shown great promise for speech enhancement under adverse acoustic conditions.
Hsinyu Chang   +3 more
doaj   +1 more source

Pricing Excess-of-loss Reinsurance Contracts Against Catastrophic Loss [PDF]

open access: yes
This paper develops a pricing methodology and pricing estimates for the proposed Federal excess-of- loss (XOL) catastrophe reinsurance contracts.
J. David Cummins   +2 more
core  

Estimating moments of a selected Pareto population under asymmetric scale invariant loss function

open access: yes, 2018
Consider independent random samples from (k≥2) Pareto populations with the same known shape parameter but different scale parameters. Let Xi be the smallest observation of the ith sample. The natural selection rule which selects the population associated
Al-Mosawi, Riyadh Rustom   +1 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

YOLO-BFRV: An Efficient Model for Detecting Printed Circuit Board Defects

open access: yesSensors
The small area of a printed circuit board (PCB) results in densely distributed defects, leading to a lower detection accuracy, which subsequently impacts the safety and stability of the circuit board.
Jiaxin Liu   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Lightweight Improved YOLOv5s-CGhostnet for Detection of Strawberry Maturity Levels and Counting

open access: yesAgriEngineering
A lightweight strawberry detection and localization algorithm plays a crucial role in enabling the harvesting robot to effectively harvest strawberries.
Niraj Tamrakar   +7 more
doaj   +1 more source

Integration of Taguchi's loss function with quality control charts

open access: yes, 2014
Statistical Process Control has been used broadly in industries, and quality control charts are key tool in SPC, which are using to keep the process under control and continue the process improvement.
Rabiee, Ali
core  

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