Results 61 to 70 of about 7,181,199 (327)
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Improving the maize crop row navigation line recognition method of YOLOX
The accurate identification of maize crop row navigation lines is crucial for the navigation of intelligent weeding machinery, yet it faces significant challenges due to lighting variations and complex environments.
Hailiang Gong, Weidong Zhuang, Xi Wang
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Colposcopic Image Segmentation Based on Feature Refinement and Attention
The current computer-aided diagnosis for cervical cancer screening encounters issues with missing detailed information during colposcopic image segmentation and incomplete edge delineation.
Yuxi He +4 more
doaj +1 more source
Common filaggrin gene loss-of-function variants are associated with skin cancer risk [PDF]
Ayodele Adelanwa +3 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
DRBD-YOLOv8: A Lightweight and Efficient Anti-UAV Detection Model
Interest in anti-UAV detection systems has increased due to growing concerns about the security and privacy issues associated with unmanned aerial vehicles (UAVs).
Panpan Jiang +5 more
doaj +1 more source
We study whether forecasts of the rate of change of the price of oil are rational. To this end, we consider a model that allows the shape of forecasters’ loss function to be studied.
Christian Pierdzioch +1 more
doaj +1 more source

