Results 191 to 200 of about 1,547,225 (303)

Intracranial aneurysm segmentation with nnU-net: utilizing loss functions and automated vessel extraction. [PDF]

Vessel Plus
Orouskhani M, Firoozeh N, Wang H, Wang Y, Shi H, Li W, Sun B, Zhang J, Li X, Zhao H, Mossa-Basha M, Hwang JN, Zhu C.   +12 more
europepmc   +1 more source

Region of interest-specific loss functions improve T₂ quantification with ultrafast T₂ mapping MRI sequences in knee, hip and lumbar spine. [PDF]

Sci Rep, 2022
Tolpadi AA, Han M, Calivà F, Pedoia V, Majumdar S.   +4 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A comparative study of loss functions and attention mechanisms in landslide semantic segmentation using U-Net. [PDF]

Sci Rep
Hegde VB, Girisha S, Shetty DK, Sughosh P, Maddodi BS, Savitha G, Balakrishnan JM.   +6 more
europepmc   +1 more source

A Physics-Informed Convolutional Neural Network with Custom Loss Functions for Porosity Prediction in Laser Metal Deposition. [PDF]

Sensors (Basel), 2022
McGowan E, Gawade V, Guo WG.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Deep-Learning-Based 3D Dose Distribution Prediction for VMAT Lung Cancer Treatment Using an Enhanced UNet3D Architecture with Composite Loss Functions. [PDF]

Bioengineering (Basel)
Mak PCY, Kong L, Chan LWC.
europepmc   +1 more source

Pitfalls in modeling loss given default of bank loans [PDF]

The parameter loss given default (LGD) of loans plays a crucial role for risk-based decision making of banks including risk-adjusted pricing. Depending on the quality of the estimation of LGDs, banks can gain significant competitive advantage.
Gürtler, Marc, Hibbeln, Martin
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Automated segmentation of COVID-19 lesions in CT scans using attention U-net with hybrid loss functions. [PDF]

Sci Rep
Bakheet S, Youssef R, Mofaddel MH, Hassan M, Alshehri A.   +4 more
europepmc   +1 more source