Results 171 to 180 of about 6,924,037 (250)

Intracranial aneurysm segmentation with nnU-net: utilizing loss functions and automated vessel extraction. [PDF]

Vessel Plus
Orouskhani M, Firoozeh N, Wang H, Wang Y, Shi H, Li W, Sun B, Zhang J, Li X, Zhao H, Mossa-Basha M, Hwang JN, Zhu C.   +12 more
europepmc   +1 more source

A Physics-Informed Convolutional Neural Network with Custom Loss Functions for Porosity Prediction in Laser Metal Deposition. [PDF]

Sensors (Basel), 2022
McGowan E, Gawade V, Guo WG.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A comparative study of loss functions and attention mechanisms in landslide semantic segmentation using U-Net. [PDF]

Sci Rep
Hegde VB, Girisha S, Shetty DK, Sughosh P, Maddodi BS, Savitha G, Balakrishnan JM.   +6 more
europepmc   +1 more source

Region of interest-specific loss functions improve T₂ quantification with ultrafast T₂ mapping MRI sequences in knee, hip and lumbar spine. [PDF]

Sci Rep, 2022
Tolpadi AA, Han M, Calivà F, Pedoia V, Majumdar S.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Deep-Learning-Based 3D Dose Distribution Prediction for VMAT Lung Cancer Treatment Using an Enhanced UNet3D Architecture with Composite Loss Functions. [PDF]

Bioengineering (Basel)
Mak PCY, Kong L, Chan LWC.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Automated segmentation of COVID-19 lesions in CT scans using attention U-net with hybrid loss functions. [PDF]

Sci Rep
Bakheet S, Youssef R, Mofaddel MH, Hassan M, Alshehri A.   +4 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source