Results 31 to 40 of about 6,924,037 (250)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

KINNTREX: a neural network to unveil protein mechanisms from time-resolved X-ray crystallography

IUCrJ
Here, a machine-learning method based on a kinetically informed neural network (NN) is introduced. The proposed method is designed to analyze a time series of difference electron-density maps from a time-resolved X-ray crystallographic experiment.
Gabriel Biener, Tek Narsingh Malla, Peter Schwander, Marius Schmidt   +3 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Rapid Identification and Accurate Localization of Walnut Trunks Based on TIoU-YOLOv8n-Pruned

Agriculture
Visual perception has become a prerequisite for the operation of automated walnut vibration harvesting robots under complex orchard conditions. This study proposes an effective trunk target detection algorithm, TIoU-YOLOv8n-Pruned, based on YOLOv8n ...
Chenchen Ye, Yan Xu, Jianping Zhou, Chengcheng Li, Fubao Fang, Zhengyang Jin   +5 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

A Hybrid Minkowski-Log-Cosh Loss Function for Robust LSTM-Based Time Series Forecasting

IEEE Access
Reliable time-series forecasting remains challenging due to noise and data irregularities that degrade model performance. Although Long Short-Term Memory (LSTM) networks effectively capture temporal dependencies, their accuracy depends critically on the ...
Kouyakou-Abalo Simsoba, Ngesa Oscar, Thomas Mageto   +2 more
doaj   +1 more source

The Logical Consistency of Simultaneous Agnostic Hypothesis Tests

Entropy, 2016
Simultaneous hypothesis tests can fail to provide results that meet logical requirements. For example, if A and B are two statements such that A implies B, there exist tests that, based on the same data, reject B but not A.
Luís G. Esteves, Rafael Izbicki, Julio M. Stern, Rafael B. Stern   +3 more
doaj   +1 more source

Estimations For The Odd Weibull Distribution under Progressive Type-II Right Censored Samples

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2020
In this study, We introducedperformances Maximum Likelihood (ML) and Bayes estimation under LINEX, GENTROPYand SQUARED loss functions results concerning a progressively type-II censoredsamples for parameters of OddW distribution.
Gülcan Gencer, Kerem Gencer
doaj   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source