Results 181 to 190 of about 7,541,076 (252)

SemanticST: A Scalable Multi‐Contextual Graph Learning Framework for Uncovering Spatial Niches and Robust Multi‐Sample Integration in Spatial Transcriptomics

open access: yesAdvanced Science, EarlyView.
Technical limitations often let dominant signals overshadow rare cell types and fine‐grained heterogeneity in spatial transcriptomics. SemanticST, a graph neural network using multi‐semantic graph fusion and a novel min‐cut loss, recovers these subtle patterns.
Roxana Zahedi   +7 more
wiley   +1 more source

Human-like scene graph generation and evaluation. [PDF]

open access: yesMultimed Tools Appl
Milewski V, Moens MF, Trusca MM.
europepmc   +1 more source

Trustworthy Multimodal Attention Framework for Creep Rupture Life Prediction Under Data‐Scarce Conditions: A Case Study on IN718

open access: yesAdvanced Science, EarlyView.
An attention‐based multimodal deep learning framework is developed to predict the creep life of Ni‐based superalloys by fusing processing parameters with microstructural micrographs. The model achieves high accuracy (R2 = 0.92), aligns with metallurgical principles by capturing δ‐phase influence, and incorporates uncertainty quantification, offering a ...
Haopeng Lv   +10 more
wiley   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

open access: yesAdvanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao   +6 more
wiley   +1 more source

Diabetes Technology in the School Setting for Preschool-Aged Children. [PDF]

open access: yesJ Diabetes Sci Technol
Gupta RM   +6 more
europepmc   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

open access: yesAdvanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen   +12 more
wiley   +1 more source

Training a force field for proteins and small molecules from scratch. [PDF]

open access: yesChem Sci
Blanco-González A   +3 more
europepmc   +1 more source

Toward Material‐Specific Peptides From in Silico Guided Peptide Engineering to Target PET in the Presence of PS

open access: yesAdvanced Science, EarlyView.
This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka   +3 more
wiley   +1 more source

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