Results 201 to 210 of about 177,318 (256)

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Treatment outcomes among tuberculosis patients with co-morbidities at Ghana's premier national referral centre: a retrospective cross-sectional study. [PDF]

BMC Infect Dis
Hackman HK, Mensah AC, Annison L, Arhin RE, Aidoo EK, Osei-Adjei G, Addo N, Sagoe AE, Appiah-Mends F.   +8 more
europepmc   +1 more source

Dielectric‐Confinement‐Induced in‐Plane Photoelectric Anisotropy in Isotropic Quasi‐1D γ‐GaS Nanoribbon

Advanced Science, EarlyView.
We investigate the geometry‐governed optoelectronic anisotropy arising from dielectric confinement in quasi‐1D γ‐GaS nanoribbons with intrinsically isotropic atomic structures. Dielectric mismatch between the nanoribbon and its surroundings leads to a general polarization‐dependent photoresponse during near‐field scattering.
Jiawei Jing, Jiamei Chen, Xing Xin, Peisong Peng, Zhihao Wu, Weiheng Zhong, Hanyu Zhang, Wanfu Shen, Jihua Zhang, Yuwei Shan, Yuanzheng Li, Xingang Zhao, Wei Xin, Fang Wang, Weida Hu, Haiyang Xu, Yichun Liu   +16 more
wiley   +1 more source

Transformer-Based Nonlinear Blind Source Separation for Anti-Jamming in DSSS Satellite Communications. [PDF]

Sensors (Basel)
Sun X, Li C, Li J, Su Q.
europepmc   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source

Neural investigation of default effects on decision-making under uncertainty. [PDF]

Sci Rep
Yu J, Liu X, Yu J, Wang Y.
europepmc   +1 more source

Evaluation of an Augmented-Reality Head-Mounted Display Among Patients With Glaucomatous Tunnel Vision. [PDF]

Transl Vis Sci Technol
Huang H, Lin J, Li Z, Han J, Tang J, Luo M, Zhu Y, Jin L, Tu S, Li Y, Zhuo Y.   +10 more
europepmc   +1 more source

Automated Detection of Quality Deviations in Poultry Processing Using Step-Specific YOLOv12 Models. [PDF]

Foods
Einsiedel D, Vita M, Kaltenecker F, Dunnewind B, Meulendijks J, Krupitzer C.   +5 more
europepmc   +1 more source

Convergence for Inactivation of TGFβ Signaling Is a Common Feature of Advanced Pancreatic Cancer. [PDF]

Cancer Discov
Hong J, Kohutek ZA, Zhang H, Lecomte N, Karnoub ER, Kappagantula R, Wood LD, O'Reilly EM, Reyngold M, Crane CH, Iacobuzio-Donahue CA.   +10 more
europepmc   +1 more source

Adapting tree-based multiple imputation methods for multilevel data? A simulation study. [PDF]

Behav Res Methods
Föge N, Schwerter J, Gurtskaia K, Pauly M, Doebler P.   +4 more
europepmc   +1 more source