Results 61 to 70 of about 389,923 (287)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Multiscalar Control Based Airgap Flux Optimization of Induction Motor for Loss Minimization

open access: yesIEEE Access
Based on the induction motor model, considering the core loss resistance that accounts for magnetic characteristic saturation, a speed control approach is devised with an adaptive full-order (AFO) speed observer.
Tadele Ayana   +2 more
doaj   +1 more source

Increasing NER Recall with Minimal Precision Loss [PDF]

open access: yes2013 European Intelligence and Security Informatics Conference, 2013
Named Entity Recognition (NER) is broadly used as a first step toward the interpretation of text documents. However, for many applications, such as forensic investigation, recall is currently inadequate, leading to loss of potentially important information. Entity class ambiguity cannot be resolved reliably due to the lack of context information or the
Kuperus, Jasper   +2 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Analytical Loss Minimization Control for IPMSM Using Linearized Torque and Loss Modeling

open access: yesIEEE Access
Copper loss minimization schemes are widely used to control interior permanent magnet synchronous motors. In the field-weakening region, the maximum torque per ampere cannot be used due to the voltage limit set by the inverter DC-link voltage.
Bumun Jung   +3 more
doaj   +1 more source

PAC-Bayesian Theory Meets Bayesian Inference [PDF]

open access: yes, 2016
We exhibit a strong link between frequentist PAC-Bayesian risk bounds and the Bayesian marginal likelihood. That is, for the negative log-likelihood loss function, we show that the minimization of PAC-Bayesian generalization risk bounds maximizes the ...
Bach, Francis   +3 more
core   +3 more sources

Learned Perceptual Image Enhancement

open access: yes, 2017
Learning a typical image enhancement pipeline involves minimization of a loss function between enhanced and reference images. While L1 and L2 losses are perhaps the most widely used functions for this purpose, they do not necessarily lead to perceptually
Milanfar, Peyman, Talebi, Hossein
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Adapted Volt-VAr Extremum-Seeking Method for Voltage Regulation and Loss Minimization in Low Voltage Distribution Networks

open access: yesIEEE Access
The high penetration of Distributed Generation (DG) in the low-voltage distribution grid has raised several concerns in recent years, mainly regarding overvoltage at the buses caused by the reversal of active power flow.
J. H. S. Carvalho   +3 more
doaj   +1 more source

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