Results 221 to 230 of about 91,338 (344)

Autoinflammation in patients with leukocytic CBL loss of heterozygosity is caused by constitutive ERK-mediated monocyte activation. [PDF]

J Clin Invest
Bohlen J, Bagarić I, Vatovec T, Ogishi M, Ahmed SF, Cederholm A, Buetow L, Sobrino S, Le Floc'h C, Arango-Franco CA, Seabra L, Michelet M, Barzaghi F, Leardini D, Saettini F, Vendemini F, Baccelli F, Catala A, Gambineri E, Veltroni M, Aguilar de la Red Y, Rice GI, Consonni F, Berteloot L, Largeaud L, Conti F, Roullion C, Masson C, Bessot B, Seeleuthner Y, Le Voyer T, Rinchai D, Rosain J, Neehus AL, Erazo-Borrás L, Li H, Janda Z, Cho EJ, Muratore E, Soudée C, Lainé C, Delabesse E, Goulvestre C, Ma CS, Puel A, Tangye SG, André I, Bole-Feysot C, Abel L, Erlacher M, Zhang SY, Béziat V, Lagresle-Peyrou C, Six E, Pasquet M, Alsina L, Aiuti A, Zhang P, Crow YJ, Landegren N, Masetti R, Huang DT, Casanova JL, Bustamante J.   +63 more
europepmc   +1 more source

Case Report: A Novel Pathomechanism in PEComa by the Loss of Heterozygosity of TP53. [PDF]

Front Oncol, 2022
Butz H, Lövey J, Szentkereszty M, Bozsik A, Tóth E, Patócs A.   +5 more
europepmc   +1 more source

MAINTENANCE AND LOSS OF HETEROZYGOSITY IN A THELYTOKOUS LINEAGE OF HONEY BEES (APIS MELLIFERA CAPENSIS)

Evolution; international journal of organic evolution, 2012
F. Goudie, M. Allsopp, M. Beekman, P. Oxley, Ju-Rak Lim, B. Oldroyd   +5 more
semanticscholar   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

KRAS Loss of Heterozygosity Promotes MAPK-Dependent Pancreatic Ductal Adenocarcinoma Initiation and Induces Therapeutic Sensitivity to MEK Inhibition. [PDF]

Cancer Res
Fey SK, Najumudeen AK, Watt DM, Millett LM, Ford CA, Gilroy K, Simpson RJ, McLay K, Upstill-Goddard R, Chang D, Clark W, Nixon C, Birch JL, Barry ST, Morton JP, Campbell AD, Sansom OJ.   +16 more
europepmc   +1 more source

Genome-scale patterns in the loss of heterozygosity incidence in Saccharomyces cerevisiae. [PDF]

Genetics, 2022
Tutaj H, Pirog A, Tomala K, Korona R.
europepmc   +1 more source

Loss of heterozygosity on chromosome 10, 13q(Rb), 17p, and p53 gene mutations in human brain gliomas

, 1995
Seung‐Hoon Lee, Jong‐Hyun Kim, Chang Hun Rhee, Young Soon Kang, Je Ho Lee, Seok Il Hong, Kil Soo Choi   +6 more
openalex   +1 more source

Genetic Instability and Aberrant DNA Methylation in Chronic Hepatitis and Cirrhosis—A Comprehensive Study of Loss of Heterozygosity and Microsatellite Instability at 39 Loci and DNA Hypermethylation on 8 CpG Islands in Microdissected Specimens From Patients With Hepatocellular Carcinoma [PDF]

, 2000
Yutaka Kondo, Yae Kanai, Michiie Sakamoto, Masashi Mizokami, Ryuzo Ueda, Setsuo Hirohashi   +5 more
openalex   +1 more source

Exome sequencing-based copy-number variation and loss of heterozygosity detection: ExomeCNV

Bioinform., 2011
J. Sathirapongsasuti, Hane Lee, B. Horst, G. Brunner, A. Cochran, S. Binder, John Quackenbush, S. Nelson   +7 more
semanticscholar   +1 more source

Mechanism and role of regulated cell death in tumor immunity and immunotherapy

Cancer Communications, EarlyView.
Abstract Cancer immune checkpoint inhibitors (ICIs) have brought breakthroughs, but only about one‐third of cancer patients benefit from ICIs. In recent years, targeting non‐apoptotic regulated cell death (RCD) subtypes, such as ferroptosis, necroptosis, autophagy, cuproptosis, and pyroptosis, has emerged as a novel strategy in cancer therapy due to ...
Jingwen Hu, Yan Li, Bingjie Lian, Yitao Mao, Luqing Zhao   +4 more
wiley   +1 more source