Results 51 to 60 of about 7,537,728 (295)

A Parametric Blade Design Method for High-Speed Axial Compressor

open access: yesAerospace, 2021
The blade geometry design method is an important tool to design high performance axial compressors, expected to have large design space while limiting the quantity of design variables to a suitable level for usability.
Hengtao Shi
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Urban Flood Susceptibility Mapping for Toronto, Canada, Using Supervised Regression and Machine Learning Models

open access: yesJournal of Flood Risk Management
Floods are one of the most devastating natural hazards, causing adverse effects on human life, well‐being, property, and the environment. The application of five machine‐learning techniques in pluvial flood susceptibility mapping was investigated using ...
Baljeet Kaur   +5 more
doaj   +1 more source

Grey wolf optimisation algorithm for solving distribution network reconfiguration considering distributed generators simultaneously

open access: yesInternational Journal of Sustainable Energy, 2022
This article represents an application of the grey wolf optimisation (GWO) algorithm to solve the most optimistic combinatorial problems for optimal distribution network reconfiguration (DNR) and allocation of distributed generators (DGs) in a system. In
Harish Kumar Pujari   +1 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Mapping Flood Hazard Across Mainland China Through a Physics‐Based Global Flood Model With Embedded Reservoir Operation Scheme

open access: yesJournal of Flood Risk Management
China has complex topography, diverse flood mechanisms, and high population exposure, making it highly vulnerable to flooding, highlighting the need for robust national‐scale hazard assessments to identify flood‐prone regions.
Jayesh Parmar   +4 more
doaj   +1 more source

Evaluation of Injection Strategies in Supersonic Nozzle Flow

open access: yesAerospace, 2021
The ability to manipulate shock patterns in a supersonic nozzle flow with fluidic injection is investigated numerically using Large Eddy Simulations.
Bernhard Semlitsch, Mihai Mihăescu
doaj   +1 more source

Loss of Genetic Redundancy in Reductive Genome Evolution

open access: yesPLoS Computational Biology, 2011
Biological systems evolved to be functionally robust in uncertain environments, but also highly adaptable. Such robustness is partly achieved by genetic redundancy, where the failure of a specific component through mutation or environmental challenge can be compensated by duplicate components capable of performing, to a limited extent, the same ...
André G. Mendonça   +2 more
openaire   +4 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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