Results 61 to 70 of about 7,537,728 (295)

Harm reduction among injecting drug users - evidence of effectiveness [PDF]

, 2010
This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Hutchinson, Sharon, Kimber, Jo, Palmateer, Norah, Goldberg, David, Rhodes, Tim, Hickman, Matthew   +5 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Occurrence and Levels of Mycotoxins in On-Farm-Stored Sesame in Major Growing Districts of Ethiopia

Agriculture
Mycotoxins in sesame seeds pose a significant risk to both food safety and Ethiopia’s economy. The purpose of this study was to determine the presence and concentrations of mycotoxins in sesame seeds kept on farms in Ethiopia’s key sesame-producing areas.
Samuel Alemayehu, Fetien Abay Abera, Kiros-Meles Ayimut, Jagger Harvey, Rizana Mahroof, Bhadriraju Subramanyam, Jonathan Ulmer, Richard Edema   +7 more
doaj   +1 more source

Development of the system of management accounting of costs of the railway transport complex

Вестник Научно-исследовательского института железнодорожного транспорта, 2017
In order to improve the efficiency of long distance transport, it is necessary for all participants in the process to optimize the costs of infrastructure services by introducing advanced technologies for the organization of the transportation process ...
O. F. Miroshnichenko, A. E. Oginskaya
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Recensione a: Sarah Rubin Blanshei, "Politica e Giustizia a Bologna nel tardomedioevo"

, 2018
Si tratta della recensione del libro pubblicato da Sarah Rubin Blanshei, come si può vedere a partire dal titolo del ...
Edward Loss, LOSS, EDWARD
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Seamless Integration of Active Antenna With Improved Power Efficiency

IEEE Access, 2020
Loss reduction to improve the power efficiency in active integrated antenna (AIA) is a key design drive. This paper first analyzes the loss mechanism in a convention AIA structure. A new integration scheme of a GaN power amplifier (PA) transistor with an
Yunlong Lu, Qing Liu, Yi Wang, Peter Gardner, Wang He, Yi Chen, Jifu Huang, Taijun Liu   +7 more
doaj   +1 more source